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Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.

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Title: Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.
Authors: Migeot J; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Metropolitan Region of Santiago,  , Chile.; Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland., Wen O; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Metropolitan Region of Santiago,  , Chile., Gonzalez-Gomez R; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Metropolitan Region of Santiago,  , Chile., Hernandez H; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Metropolitan Region of Santiago,  , Chile., Aguillon D; Grupo de Neurociencias de Antioquia Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia., Avila-Funes JA; Dirección de Enseñanza, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France., Behrens MI; Centro de Investigación Clínica Avanzada (CICA) - Hospital Clínico Universidad de Chile, Santiago Chile, Independencia, Santiago, Chile.; Departamento de Neurología y Neurocirugía, Hospital Clínico Universidad de Chile, Independencia, Santiago, Chile.; Departamento de Neurociencia, Facultad de Medicina, Universidad de Chile, Independencia, Santiago, Chile.; Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago-Universidad del Desarrollo, Santiago, Chile., Bruno MA; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.; Instituto de Ciencias Biomédicas (ICBM), Facultad de Ciencias Médicas, Universidad Católica de Cuyo, San Juan, Argentina., Custodio N; Unidad de diagnóstico de deterioro cognitivo y prevención de demencia, Instituto Peruano de Neurociencias, Lima, Perú.; Unidad de investigación, Equilibria, Lima, Perú., Delgado C; Departamento de Neurología y Neurocirugía. Hospital Clínico Universidad de Chile, Santiago, Chile.; Departamento de Neurociencia Facultad de medicina Universidad de Chile, Santiago, Chile., Duran-Aniotz C; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Metropolitan Region of Santiago,  , Chile., Duron-Reyes D; Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland.; Alzheimer Aguascalientes Family Foundation, Aguascalientes, Mexico., García AM; Departamento de Lingüística y Literatura, Facultad de Humanidades, Universidad de Santiago de Chile, Santiago, Chile.; Global Brain Health Institute, University of California, San Francisco, California, USA.; Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina., Godoy ME; Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina., Hu K; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts, USA.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Lawlor B; Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland., Li P; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts, USA.; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Maito MA; Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina., Matallana DL; Departamento de Salud Mental, Hospital Universitario Fundación Santa Fe, Bogotá, Colombia.; Centro de Memoria y Cognición, Hospital Universitario San Ignacio, Bogotá, Colombia., Miller B; Global Brain Health Institute, University of California, San Francisco, California, USA.; Department of Neurology, Memory and Aging Center, University of California, San Francisco, California, USA., de Oliveira MO; Global Brain Health Institute, University of California, San Francisco, California, USA.; Cognitive Neurology and Behavioral Unit (GNCC), University of São Paulo, São Paulo, Brazil., Pina-Escudero SD; Global Brain Health Institute, University of California, San Francisco, California, USA.; Department of Neurology, Memory and Aging Center, University of California, San Francisco, California, USA., Possin KL; Global Brain Health Institute, University of California, San Francisco, California, USA.; Department of Neurology, Memory and Aging Center, University of California, San Francisco, California, USA., Resende EPF; Global Brain Health Institute, University of California, San Francisco, California, USA.; Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Reyes P; Pontificia Universidad Javeriana, Bogotá, D.C., Colombia., Santamaria-Garcia H; Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.; Hospital Universitario San Ignacio, Center for Memory and Cognition, Intellectus, Bogotá, D.C, Colombia., Slachevsky A; Geroscience Center for Brain Health and Metabolism (GERO), Santiago de Chile, Metropolitan Region of Santiago, Chile.; Memory and Neuropsychiatric Center (CMYN), Neurology Department, Hospital del Salvador & Faculty of Medicine, University of Chile, Santiago de Chile, Chile.; Neuropsychology and Clinical Neuroscience Laboratory (LANNEC), Physiopathology Program - Institute of Biomedical Sciences, Neuroscience and East Neuroscience Departments, Faculty of Medicine, University of Chile, Santiago de Chile, Chile.; Departamento de Medicina, Servicio de Neurología, Clínica Alemana-Universidad del Desarrollo, Santiago de Chile, Metropolitan Region of Santiago, Chile., Takada LT; Cognitive Neurology and Behavioral Unit (GNCC), University of São Paulo, São Paulo, Brazil., Vergara P; Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland., Yaffe K; Global Brain Health Institute, University of California, San Francisco, California, USA.; Department of Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Yokoyama JS; Global Brain Health Institute, University of California, San Francisco, California, USA.; Department of Neurology, Memory and Aging Center, University of California, San Francisco, California, USA.; Department of Epidemiology & Biostatistics, University of California, San Francisco, California, USA., Romero-Ortuño R; Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland.; Discipline of Medical Gerontology, School of Medicine, Trinity College Dublin,  , Ireland., Ibanez A; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibañez, Santiago de Chile, Metropolitan Region of Santiago,  , Chile.; Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland.; Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.; Department of Biophysics, School of Medicine, Istanbul Medipol University, Istanbul, Türkiye.; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Apr; Vol. 22 (4), pp. e71232.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1552-5279
DOI:10.1002/alz.71232