Inhibition of GATA4 and MEF2C Induced by Hypo-Acetylation of Histone H3 Partly Reverse Heart Failure in Mice.

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Title: Inhibition of GATA4 and MEF2C Induced by Hypo-Acetylation of Histone H3 Partly Reverse Heart Failure in Mice.
Authors: Gan X; Department of Cardiovascular Medicine, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Key Cardiovascular Specialty, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Key Laboratory of Children's Important Organ Development and Diseases of Chongqing Municipal Health Commission, National Clinical Research Center for Child Health and Disorders Children's Hospital of Chongqing Medical University Chongqing China., Pan B; Department of Cardiovascular Medicine, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Key Cardiovascular Specialty, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Key Laboratory of Children's Important Organ Development and Diseases of Chongqing Municipal Health Commission, National Clinical Research Center for Child Health and Disorders Children's Hospital of Chongqing Medical University Chongqing China., Liu L; Department of Cardiovascular Medicine, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Key Cardiovascular Specialty, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Key Laboratory of Children's Important Organ Development and Diseases of Chongqing Municipal Health Commission, National Clinical Research Center for Child Health and Disorders Children's Hospital of Chongqing Medical University Chongqing China., Li M; Department of Cardiovascular Medicine, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Key Cardiovascular Specialty, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Key Laboratory of Children's Important Organ Development and Diseases of Chongqing Municipal Health Commission, National Clinical Research Center for Child Health and Disorders Children's Hospital of Chongqing Medical University Chongqing China., Sun H; Department of Cardiovascular Medicine, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Key Cardiovascular Specialty, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Key Laboratory of Children's Important Organ Development and Diseases of Chongqing Municipal Health Commission, National Clinical Research Center for Child Health and Disorders Children's Hospital of Chongqing Medical University Chongqing China.
Source: Pediatric discovery [Pediatr Discov] 2026 Mar 27; Vol. 4 (1), pp. e70045. Date of Electronic Publication: 2026 Mar 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Australia, Ltd. on behalf of Children's Hospital of Chongqing Medical University Country of Publication: Australia NLM ID: 9918751188406676 Publication Model: eCollection Cited Medium: Internet ISSN: 2835-5598 (Electronic) Linking ISSN: 2835558X NLM ISO Abbreviation: Pediatr Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2835-5598
DOI:10.1002/pdi3.70045