Impact of the gut microbiome on hepatic cytochrome P450 3A4 (CYP3A4) in humanized pregnane X receptor-constitutive androstane receptor-CYP3A4/3A7 mice.
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| Title: | Impact of the gut microbiome on hepatic cytochrome P450 3A4 (CYP3A4) in humanized pregnane X receptor-constitutive androstane receptor-CYP3A4/3A7 mice. |
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| Authors: | Liem J; Department of Pharmaceutics, University of Washington, Seattle, Washington., Chen X; Department of Pharmaceutics, University of Washington, Seattle, Washington., Lim JJ; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), Seattle, Washington., Mao Q; Department of Pharmaceutics, University of Washington, Seattle, Washington., Cui JY; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), Seattle, Washington., Lin YS; Department of Pharmaceutics, University of Washington, Seattle, Washington. Electronic address: yvonlin@uw.edu. |
| Source: | Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2026 May; Vol. 54 (5), pp. 100284. Date of Electronic Publication: 2026 Mar 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42025145 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Impact of the gut microbiome on hepatic cytochrome P450 3A4 (CYP3A4) in humanized pregnane X receptor-constitutive androstane receptor-CYP3A4/3A7 mice. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Liem+J%22">Liem J</searchLink>; Department of Pharmaceutics, University of Washington, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Pharmaceutics, University of Washington, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Lim+JJ%22">Lim JJ</searchLink>; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Mao+Q%22">Mao Q</searchLink>; Department of Pharmaceutics, University of Washington, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Cui+JY%22">Cui JY</searchLink>; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Lin+YS%22">Lin YS</searchLink>; Department of Pharmaceutics, University of Washington, Seattle, Washington. Electronic address: yvonlin@uw.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229421550%22">Drug metabolism and disposition: the biological fate of chemicals</searchLink> [Drug Metab Dispos] 2026 May; Vol. 54 (5), pp. 100284. <i>Date of Electronic Publication: </i>2026 Mar 26. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Pharmacology+and+Experimental+Therapeutics%2C+etc%2E]%22">American Society for Pharmacology and Experimental Therapeutics, etc.] </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9421550 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-009X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200909556%22">00909556 </searchLink><i>NLM ISO Abbreviation: </i>Drug Metab Dispos <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42025145 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.dmd.2026.100284 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 100284 Titles: – TitleFull: Impact of the gut microbiome on hepatic cytochrome P450 3A4 (CYP3A4) in humanized pregnane X receptor-constitutive androstane receptor-CYP3A4/3A7 mice. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Liem J – PersonEntity: Name: NameFull: Chen X – PersonEntity: Name: NameFull: Lim JJ – PersonEntity: Name: NameFull: Mao Q – PersonEntity: Name: NameFull: Cui JY – PersonEntity: Name: NameFull: Lin YS IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2026 May Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1521-009X Numbering: – Type: volume Value: 54 – Type: issue Value: 5 Titles: – TitleFull: Drug metabolism and disposition: the biological fate of chemicals Type: main |
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