Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.
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| Title: | Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease. |
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| Authors: | Wearn A; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada., Onuska KM; Schulich Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Western University, London, ON, Canada., Shanks HRC; Schulich Medicine and Dentistry, Western University, London, ON, Canada., Gaurav R; Paris Brain Institute-ICM, Center for NeuroImaging Research-CENIR, Sorbonne Universite, CNRS, Inserm, Paris, France., Lehéricy S; Paris Brain Institute-ICM, Center for NeuroImaging Research-CENIR, Sorbonne Universite, CNRS, Inserm, Paris, France., Baracchini G; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada., Hughes C; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.; Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, Indiana, USA., Tremblay-Mercier J; Douglas Mental Health University Institute, Verdun, QC, Canada., Narayanan S; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.; McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada., Breitner J; Douglas Mental Health University Institute, Verdun, QC, Canada.; Department of Psychiatry, McGill University, Montreal, QC, Canada., Poirier J; Department of Psychiatry, McGill University, Montreal, QC, Canada., Schmitz TW; Schulich Medicine and Dentistry, Western University, London, ON, Canada.; Robarts Research Institute, Western University, London, ON, Canada.; Department of Physiology and Pharmacology, Western University, London, ON, Canada., Turner GR; Department of Psychology, York University, Toronto, ON, Canada., Spreng RN; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.; McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada.; Department of Psychiatry, McGill University, Montreal, QC, Canada.; Department of Psychology, McGill University, Montreal, QC, Canada. |
| Corporate Authors: | PREVENT‐AD Research Group |
| Source: | Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Apr; Vol. 22 (4), pp. e71427. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-5279 |
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| DOI: | 10.1002/alz.71427 |
