Multiomics analysis identifies VPA-induced changes in neural progenitor cells, ventricular-like regions, and cellular microenvironment in dorsal forebrain organoids.
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| Title: | Multiomics analysis identifies VPA-induced changes in neural progenitor cells, ventricular-like regions, and cellular microenvironment in dorsal forebrain organoids. |
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| Authors: | Yentür Z; The Heidelberg Academy of Sciences and Humanities, Heidelberg, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; International Max Planck Research School, Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Branco L; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Sarieva K; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; International Max Planck Research School, Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany., Andreeva D; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Kagermeier T; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Kulka C; University of Tübingen, Tübingen, Germany., Jarboui MA; Core Facility for Medical Proteomics, Institute for Ophthalmic Research, University Clinic Tübingen, Tübingen, Germany., Colombo F; Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, Heidelberg, Germany., Diaz F; Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, Heidelberg, Germany., Collignon P; Institute of Biological and Chemical Systems - Functional Molecular Systems, Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany., Becker K; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Selhuber-Unkel C; Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, Heidelberg, Germany., Mayer S; The Heidelberg Academy of Sciences and Humanities, Heidelberg, Germany. simone.mayer@kit.edu.; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. simone.mayer@kit.edu.; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany. simone.mayer@kit.edu.; Institute of Biological and Chemical Systems - Functional Molecular Systems, Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany. simone.mayer@kit.edu. |
| Source: | Molecular psychiatry [Mol Psychiatry] 2026 Apr 24. Date of Electronic Publication: 2026 Apr 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42032298 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Multiomics analysis identifies VPA-induced changes in neural progenitor cells, ventricular-like regions, and cellular microenvironment in dorsal forebrain organoids. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yentür+Z%22">Yentür Z</searchLink>; The Heidelberg Academy of Sciences and Humanities, Heidelberg, Germany.; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; International Max Planck Research School, Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Branco+L%22">Branco L</searchLink>; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Sarieva+K%22">Sarieva K</searchLink>; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; International Max Planck Research School, Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Andreeva+D%22">Andreeva D</searchLink>; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Kagermeier+T%22">Kagermeier T</searchLink>; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany.; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Kulka+C%22">Kulka C</searchLink>; University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jarboui+MA%22">Jarboui MA</searchLink>; Core Facility for Medical Proteomics, Institute for Ophthalmic Research, University Clinic Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Colombo+F%22">Colombo F</searchLink>; Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Diaz+F%22">Diaz F</searchLink>; Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Collignon+P%22">Collignon P</searchLink>; Institute of Biological and Chemical Systems - Functional Molecular Systems, Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+K%22">Becker K</searchLink>; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Selhuber-Unkel+C%22">Selhuber-Unkel C</searchLink>; Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mayer+S%22">Mayer S</searchLink>; The Heidelberg Academy of Sciences and Humanities, Heidelberg, Germany. simone.mayer@kit.edu.; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. simone.mayer@kit.edu.; Systemic Cellular Neurobiology, Zoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany. simone.mayer@kit.edu.; Institute of Biological and Chemical Systems - Functional Molecular Systems, Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany. simone.mayer@kit.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Apr 24. <i>Date of Electronic Publication: </i>2026 Apr 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42032298 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41380-026-03585-5 Languages: – Code: eng Text: English Titles: – TitleFull: Multiomics analysis identifies VPA-induced changes in neural progenitor cells, ventricular-like regions, and cellular microenvironment in dorsal forebrain organoids. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yentür Z – PersonEntity: Name: NameFull: Branco L – PersonEntity: Name: NameFull: Sarieva K – PersonEntity: Name: NameFull: Andreeva D – PersonEntity: Name: NameFull: Kagermeier T – PersonEntity: Name: NameFull: Kulka C – PersonEntity: Name: NameFull: Jarboui MA – PersonEntity: Name: NameFull: Colombo F – PersonEntity: Name: NameFull: Diaz F – PersonEntity: Name: NameFull: Collignon P – PersonEntity: Name: NameFull: Becker K – PersonEntity: Name: NameFull: Selhuber-Unkel C – PersonEntity: Name: NameFull: Mayer S IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 04 Text: 2026 Apr 24 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5578 Titles: – TitleFull: Molecular psychiatry Type: main |
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