Methylation heterogeneity of the AQP1 promoter as a candidate prognostic biomarker in cholangiocarcinoma.

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Title: Methylation heterogeneity of the AQP1 promoter as a candidate prognostic biomarker in cholangiocarcinoma.
Authors: Yokoyama S; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Noguchi H; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Hamada T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Matsuo K; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Akahane T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.; Center for Human Genome and Gene Analysis, Kagoshima University Hospital, Kagoshima, Japan., Kitazono I; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan., Tasaki T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Murakami M; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Ohtsuka T; Department of Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Higashi M; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan., Furukawa T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Tanimoto A; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Center for Human Genome and Gene Analysis, Kagoshima University Hospital, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Center for Research of Advanced Diagnosis and Therapy of Cancer, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.
Source: Scientific reports [Sci Rep] 2026 Apr 25; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-49380-8