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Methylation heterogeneity of the AQP1 promoter as a candidate prognostic biomarker in cholangiocarcinoma.

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Title: Methylation heterogeneity of the AQP1 promoter as a candidate prognostic biomarker in cholangiocarcinoma.
Authors: Yokoyama S; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Noguchi H; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Hamada T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Matsuo K; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Akahane T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.; Center for Human Genome and Gene Analysis, Kagoshima University Hospital, Kagoshima, Japan., Kitazono I; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan., Tasaki T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Murakami M; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Ohtsuka T; Department of Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan., Higashi M; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan., Furukawa T; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan., Tanimoto A; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Center for Human Genome and Gene Analysis, Kagoshima University Hospital, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Center for Research of Advanced Diagnosis and Therapy of Cancer, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.
Source: Scientific reports [Sci Rep] 2026 Apr 25; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Methylation heterogeneity of the AQP1 promoter as a candidate prognostic biomarker in cholangiocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Yokoyama+S%22">Yokoyama S</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Noguchi+H%22">Noguchi H</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Hamada+T%22">Hamada T</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuo+K%22">Matsuo K</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Akahane+T%22">Akahane T</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.; Center for Human Genome and Gene Analysis, Kagoshima University Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Kitazono+I%22">Kitazono I</searchLink>; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Tasaki+T%22">Tasaki T</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Murakami+M%22">Murakami M</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Ohtsuka+T%22">Ohtsuka T</searchLink>; Department of Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Higashi+M%22">Higashi M</searchLink>; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Furukawa+T%22">Furukawa T</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Tanimoto+A%22">Tanimoto A</searchLink>; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Center for Human Genome and Gene Analysis, Kagoshima University Hospital, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Department of Surgical Pathology, Kagoshima University Hospital, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.; Center for Research of Advanced Diagnosis and Therapy of Cancer, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. akit09@m3.kufm.kagoshima-u.ac.jp.
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