Cellular Senescence of Patient-derived Fibroblasts Reveals the Mid-old Stage as a Critical Window for Transcriptomic Signatures Linked to Alzheimer's Disease Biomarkers and Classification.

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Title: Cellular Senescence of Patient-derived Fibroblasts Reveals the Mid-old Stage as a Critical Window for Transcriptomic Signatures Linked to Alzheimer's Disease Biomarkers and Classification.
Authors: Cho YJ; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Yoon S; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Kim Y; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Song HM; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Nam YJ; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Lee SH; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Lee S; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Shin D; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Lee SM; Department of Neurology, Ajou University School of Medicine, Suwon, Korea., Moon SY; Department of Neurology, Ajou University School of Medicine, Suwon, Korea., Kim EJ; Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, Korea., Cho SH; Department of Neurology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea., Kim BC; Department of Neurology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea., Choi SH; Department of Neurology, Inha University College of Medicine, Incheon, Korea., Seo SW; Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Kim JC; Department of Dermatology, Ajou University School of Medicine, Suwon, Korea., Park YJ; Department of Dermatology, Ajou University School of Medicine, Suwon, Korea., Kang HY; Department of Dermatology, Ajou University School of Medicine, Suwon, Korea., Lee SR; Efficacy Test Center for Mental & Behavioral Disorders, Ajou University Hospital, Suwon, Korea., Hong S; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea., Son SJ; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea.; BK21 R&E Initiative for Advanced Precision Medicine, Graduate School of Ajou University, Suwon, Korea., Hong CH; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea.; BK21 R&E Initiative for Advanced Precision Medicine, Graduate School of Ajou University, Suwon, Korea., Roh HW; Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.; Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea.; BK21 R&E Initiative for Advanced Precision Medicine, Graduate School of Ajou University, Suwon, Korea.
Source: Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology [Clin Psychopharmacol Neurosci] 2026 May 31; Vol. 24 (2), pp. 353-367. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: Korean College of Neuropsychopharmacology Country of Publication: Korea (South) NLM ID: 101207332 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1738-1088 (Print) Linking ISSN: 17381088 NLM ISO Abbreviation: Clin Psychopharmacol Neurosci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1738-1088
DOI:10.9758/cpn.25.1360