Novel piperazine-triazole hybrids as PTP1B and alpha-amylase inhibitors: synthesis, biological evaluation and computational validation through network pharmacology, molecular docking, MD simulations, DFT and MMPBSA analysis.

Saved in:
Bibliographic Details
Title: Novel piperazine-triazole hybrids as PTP1B and alpha-amylase inhibitors: synthesis, biological evaluation and computational validation through network pharmacology, molecular docking, MD simulations, DFT and MMPBSA analysis.
Authors: Haroon M; Department of Chemistry, Government College University Faisalabad Faisalabad 38000 Pakistan fawad.zahoor@gcuf.edu.pk., Kamal S; Department of Biochemistry, Government College University Faisalabad Faisalabad 38000 Pakistan., Mansha A; Department of Chemistry, Government College University Faisalabad Faisalabad 38000 Pakistan fawad.zahoor@gcuf.edu.pk., Zahoor AF; Department of Chemistry, Government College University Faisalabad Faisalabad 38000 Pakistan fawad.zahoor@gcuf.edu.pk.
Source: RSC advances [RSC Adv] 2026 Apr 27; Vol. 16 (24), pp. 21867-21895. Date of Electronic Publication: 2026 Apr 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2046-2069
DOI:10.1039/d6ra00931j