AAV2 capsid clearance and neuronal trafficking dynamics in the central nervous system.

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Title: AAV2 capsid clearance and neuronal trafficking dynamics in the central nervous system.
Authors: Gullapalli T; Undergraduate Research Program, The Ohio State University, Columbus, OH, USA.; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Willows JW; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Karkhah A; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Munjal V; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA.; Medical Student Research Program, The Ohio State College of Medicine, The Ohio State University, Columbus, OH, USA., Nimmo A; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA.; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, USA., Ceyhan KE; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Travis M; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., O'Brien A; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Rocco MT; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Taunque AS; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Townsend KL; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA., Samaranch L; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA. Lluis.Samaranch@osumc.edu.; Gene Therapy Institute, The Ohio State University, Columbus, OH, USA. Lluis.Samaranch@osumc.edu.
Source: Gene therapy [Gene Ther] 2026 Apr 30. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5462
DOI:10.1038/s41434-026-00617-1