A Muribaculaceae-enriched microbiota exacerbates TLR4-dependent Acinetobacter baumannii-induced hyperinflammatory sepsis.

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Title: A Muribaculaceae-enriched microbiota exacerbates TLR4-dependent Acinetobacter baumannii-induced hyperinflammatory sepsis.
Authors: Jang S; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea., Kim YJ; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea.; Department of Biotechnology, KRIBB School, Korea University of Science and Technology (UST), Daejeon, 34141, Republic of Korea., Park J; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea.; College of Veterinary Medicine, Chungnam National University, Daejeon, 34134, Republic of Korea., Kim D; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea., Kim TH; College of Veterinary Medicine, Chungnam National University, Daejeon, 34134, Republic of Korea., Lee S; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea., Kim DJ; College of Medicine, Chungbuk National University, Cheongju, 28644, Republic of Korea. golddj@cbnu.ac.kr.; Biomedical Research Institute, Chungbuk National University Hospital, Cheongju, 28644, Republic of Korea. golddj@cbnu.ac.kr., Ryu CM; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea. cmryu@kribb.re.kr.; Department of Biotechnology, KRIBB School, Korea University of Science and Technology (UST), Daejeon, 34141, Republic of Korea. cmryu@kribb.re.kr., Seo HW; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea. seohw01@kribb.re.kr.; Department of Functional Genomics, KRIBB School, Korea University of Science and Technology (UST), Daejeon, 34141, Republic of Korea. seohw01@kribb.re.kr.
Source: Nature communications [Nat Commun] 2026 Apr 30. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-72435-3