Antimicrobial peptide-induced inner membrane hyperpolarization is associated with antibiotic sensitization and attenuated MIC escalation in multidrug-resistant Gram-negative pathogens.
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| Title: | Antimicrobial peptide-induced inner membrane hyperpolarization is associated with antibiotic sensitization and attenuated MIC escalation in multidrug-resistant Gram-negative pathogens. |
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| Authors: | Yeh JC; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC., Hazam PK; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC.; Faculty of Pharmaceutical Science, Assam down town University, Guwahati, Assam, India., Lin YY; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC., Chang YC; Academia Sinica Cryo-EM Center, Academia Sinica, Taipei, Taiwan, ROC., Selvaraj SP; Molecular and Biological Agricultural Science Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan, ROC.; Graduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan, ROC., Li CC; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, ROC., Lin PY; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, ROC., Huang YP; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC., Chang CF; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC., You MF; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC., Chen JY; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Jiaushi, Ilan, Taiwan, ROC. zoocjy@gate.sinica.edu.tw.; The iEGG and Animal Biotechnology Center and the Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan, ROC. zoocjy@gate.sinica.edu.tw. |
| Source: | Npj antimicrobials and resistance [NPJ Antimicrob Resist] 2026 Apr 30; Vol. 4 (1). Date of Electronic Publication: 2026 Apr 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918804282606676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-8745 (Electronic) Linking ISSN: 27318745 NLM ISO Abbreviation: NPJ Antimicrob Resist Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2731-8745 |
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| DOI: | 10.1038/s44259-026-00210-x |
