View in EDS

Ion Mobility-Mass Spectrometry and Collision Induced Unfolding Reveal Linker-Payload Effects on Antibody-Drug Conjugate Higher-Order Structure and Stability.

Saved in:

Bibliographic Details
Title:	Ion Mobility-Mass Spectrometry and Collision Induced Unfolding Reveal Linker-Payload Effects on Antibody-Drug Conjugate Higher-Order Structure and Stability.
Authors:	Makey DM; Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.; Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Emmert MH; Process Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Hu H; Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Larson EJ; Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Appiah-Amponsah E; Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Regalado EL; Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Barrientos RC; Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Ruotolo BT; Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.
Source:	Bioconjugate chemistry [Bioconjug Chem] 2026 May 20; Vol. 37 (5), pp. 942-949. Date of Electronic Publication: 2026 Apr 30.
Publication Type:	Journal Article
Journal Info:	Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1520-4812
DOI:	10.1021/acs.bioconjchem.6c00018