High-resolution single-cell mapping of clonal hematopoiesis and structural variation in aplastic anemia.

Saved in:
Bibliographic Details
Title: High-resolution single-cell mapping of clonal hematopoiesis and structural variation in aplastic anemia.
Authors: Yoshida M; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pediatric Hematology and Oncology Research, Research Institute, National Center for Child Health and Development, Tokyo, Japan., Sahoo SS; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Arnold PY; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Gurnari C; Translational Hematology and Oncology Research Department, Cleveland Clinic, Cleveland, OH, USA.; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy., van Leeuwen AJCN; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Pu L; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., van Roosmalen MJ; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Chang TC; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Goodings C; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Mehmood R; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Derks LLM; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Gray N; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Boals M; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Lewis S; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Kotmayer L; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Branstetter CN; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Thota S; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Leow J; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhang W; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Li Y; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Loyd MR; Hartwell Center for Biotechnology, St. Jude Children's Research Hospital, Memphis, TN, USA., Ridout G; Hartwell Center for Biotechnology, St. Jude Children's Research Hospital, Memphis, TN, USA., Walker EV; Hartwell Center for Biotechnology, St. Jude Children's Research Hospital, Memphis, TN, USA., LaFlamme CW; Center for Pediatric Neurological Disease Research, St. Jude Children's Research Hospital, Memphis, TN, USA., Mefford HC; Center for Pediatric Neurological Disease Research, St. Jude Children's Research Hospital, Memphis, TN, USA., Brady Z; Translational Hematology and Oncology Research Department, Cleveland Clinic, Cleveland, OH, USA., Shah YB; Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Congdon RG; Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Erlacher M; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, University of Freiburg, Freiburg, Germany.; Department of Pediatrics and Adolescent Medicine, University Medical Center of Ulm, Ulm, Germany., Strahm B; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, University of Freiburg, Freiburg, Germany., Yoshimi A; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, University of Freiburg, Freiburg, Germany., Hirabayashi S; Department of Pediatrics, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Reed HD; Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Shimamura A; Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Kang G; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Chen X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Niemeyer CM; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, University of Freiburg, Freiburg, Germany., Oved JH; Department of Pediatric Transplant and Cell Therapy, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Olson TS; Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., van Boxtel R; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Maciejewski JP; Translational Hematology and Oncology Research Department, Cleveland Clinic, Cleveland, OH, USA., Babushok DV; Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wlodarski MW; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA. marcin.wlodarski@stjude.org.
Source: Nature genetics [Nat Genet] 2026 May; Vol. 58 (5), pp. 1073-1086. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-1718
DOI:10.1038/s41588-026-02587-x