Insulin production in the retina drives autocrine signalling and metabolism reprogramming of the ARPE-19, a retinal pigment epithelium cellular model.

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Title: Insulin production in the retina drives autocrine signalling and metabolism reprogramming of the ARPE-19, a retinal pigment epithelium cellular model.
Authors: Puddu A; Department of Internal Medicine and Medical Specialties, University of Genova, Genova, Italy., Balbi M; Department of Experimental Medicine, University of Genoa, Genova, Italy., Ravera S; Department of Experimental Medicine, University of Genoa, Genova, Italy. silvia.ravera@unige.it.; IRCCS Azienda Ospedaliera Metropolitana, Genova, Italy. silvia.ravera@unige.it., Panfoli I; Department of Pharmacy-(DIFAR), University of Genoa, Genova, Italy., Maggi D; Department of Internal Medicine and Medical Specialties, University of Genova, Genova, Italy.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 May 01; Vol. 83 (1). Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-026-06222-0