HBV-Induced Pyruvate Increases Lactylation of Pyruvate Kinase M2 (PKM2) at K206 to Promote Liver Fibrosis.
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| Title: | HBV-Induced Pyruvate Increases Lactylation of Pyruvate Kinase M2 (PKM2) at K206 to Promote Liver Fibrosis. |
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| Authors: | Wen W; Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China.; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Du Q; Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China.; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Li S; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Yang Y; Department of Urology, Institute of Urology, Kidney Transplant Center, West China Hospital, Sichuan University, Chengdu 610041, China., Wang X; Department of Urology, Institute of Urology, Kidney Transplant Center, West China Hospital, Sichuan University, Chengdu 610041, China., Li S; Department of Hepatology, The Second People's Hospital of Fuyang City, Fuyang 236015, China., Li Y; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Li S; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Yang C; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Xie H; The Hospital of Xidian Group, Xi'an 710077, China., Duan X; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China., Chen L; Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China.; The Hospital of Xidian Group, Xi'an 710077, China.; The Joint Laboratory on Transfusion-Transmitted Diseases (TTDs) Between Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Nanning Blood Center, Nanning Blood Center, Nanning 530007, China. |
| Source: | Pathogens (Basel, Switzerland) [Pathogens] 2026 Apr 16; Vol. 15 (4). Date of Electronic Publication: 2026 Apr 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-0817 (Electronic) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2076-0817 |
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| DOI: | 10.3390/pathogens15040431 |
