Catalase Specifically Binds Antipsychotic Clozapine: Experimental and In Silico Insights into Interactions, Complex Stability, and Dose-Dependent Enzyme Activity Modulation.

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Title: Catalase Specifically Binds Antipsychotic Clozapine: Experimental and In Silico Insights into Interactions, Complex Stability, and Dose-Dependent Enzyme Activity Modulation.
Authors: Vasović T; Department of Biochemistry, Faculty of Chemistry, University of Belgrade, 11000 Belgrade, Serbia., Radibratović M; Department of Chemistry, Institute for Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia., Spasić D; Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia., Minić S; Department of Biochemistry, Faculty of Chemistry, University of Belgrade, 11000 Belgrade, Serbia., Miljević Č; Institute of Mental Health, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia., Gligorijević N; Department of Chemistry, Institute for Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia., Nikolić M; Department of Biochemistry, Faculty of Chemistry, University of Belgrade, 11000 Belgrade, Serbia.
Source: Molecules (Basel, Switzerland) [Molecules] 2026 Apr 16; Vol. 31 (8). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-3049
DOI:10.3390/molecules31081294