PRKN/parkin-mediated control of SNCA (synuclein alpha) and chaperone-mediated autophagy are defective in cellular, mice models and Parkinson disease-affected brains.

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Title:	PRKN/parkin-mediated control of SNCA (synuclein alpha) and chaperone-mediated autophagy are defective in cellular, mice models and Parkinson disease-affected brains.
Authors:	Ramos Dos Santos L; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Duplan E; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Debord J; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Fremont G; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Minniti J; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Lauritzen I; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Mutez E; University of Lille, INSERM, CHU Lille, UMR-S 1172-LilNCog-Lille Neuroscience and Cognition, Lille, France., Leghay C; University of Lille, INSERM, CHU Lille, UMR-S 1172-LilNCog-Lille Neuroscience and Cognition, Lille, France., Chartier-Harlin MC; University of Lille, INSERM, CHU Lille, UMR-S 1172-LilNCog-Lille Neuroscience and Cognition, Lille, France., Checler F; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France., Alves da Costa C; University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 'Laboratory of Excellence (LABEX) Distalz', Valbonne, France.
Source:	Autophagy [Autophagy] 2026 May 13, pp. 1-19. Date of Electronic Publication: 2026 May 13.
Publication Type:	Journal Article
Journal Info:	Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE
Database:	MEDLINE Ultimate

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ISSN:	1554-8635
DOI:	10.1080/15548627.2026.2669458