Exposure-response modeling of QTc interval and creatine kinase-MB in healthy people and treatment-naïve adults living with HIV-1 treated with ainuovirine monotherapy or combined with lamivudine and tenofovir DF.
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| Title: | Exposure-response modeling of QTc interval and creatine kinase-MB in healthy people and treatment-naïve adults living with HIV-1 treated with ainuovirine monotherapy or combined with lamivudine and tenofovir DF. |
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| Authors: | Zhou Z; Clinical Research and Development Center, Jiangsu Aidea Pharmaceutical Co., Ltd, Yangzhou 225008, Jiangsu Province, China; Chengdu Aidea Pharmaceutical Technology Co., Ltd, Chengdu 610200, Sichuan Province, China., Zhang Y; Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China., Yun X; Clinical Research and Development Center, Jiangsu Aidea Pharmaceutical Co., Ltd, Yangzhou 225008, Jiangsu Province, China., Wu H; Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China., Qin H; Clinical Research and Development Center, Jiangsu Aidea Pharmaceutical Co., Ltd, Yangzhou 225008, Jiangsu Province, China. Electronic address: qinh@aidea.com.cn., Su B; Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China. Electronic address: binsu@ccmu.edu.cn. |
| Source: | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2026 Jul 01; Vol. 222, pp. 107544. Date of Electronic Publication: 2026 May 03. |
| Publication Type: | Journal Article; Clinical Trial, Phase I |
| Journal Info: | Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42086178 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Exposure-response modeling of QTc interval and creatine kinase-MB in healthy people and treatment-naïve adults living with HIV-1 treated with ainuovirine monotherapy or combined with lamivudine and tenofovir DF. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhou+Z%22">Zhou Z</searchLink>; Clinical Research and Development Center, Jiangsu Aidea Pharmaceutical Co., Ltd, Yangzhou 225008, Jiangsu Province, China; Chengdu Aidea Pharmaceutical Technology Co., Ltd, Chengdu 610200, Sichuan Province, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Yun+X%22">Yun X</searchLink>; Clinical Research and Development Center, Jiangsu Aidea Pharmaceutical Co., Ltd, Yangzhou 225008, Jiangsu Province, China.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.<br /><searchLink fieldCode="AU" term="%22Qin+H%22">Qin H</searchLink>; Clinical Research and Development Center, Jiangsu Aidea Pharmaceutical Co., Ltd, Yangzhou 225008, Jiangsu Province, China. Electronic address: qinh@aidea.com.cn.<br /><searchLink fieldCode="AU" term="%22Su+B%22">Su B</searchLink>; Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China. Electronic address: binsu@ccmu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229317982%22">European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences</searchLink> [Eur J Pharm Sci] 2026 Jul 01; Vol. 222, pp. 107544. <i>Date of Electronic Publication: </i>2026 May 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase I – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+B%2EV%22">Elsevier Science B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9317982 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0720 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209280987%22">09280987 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharm Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42086178 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejps.2026.107544 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 107544 Titles: – TitleFull: Exposure-response modeling of QTc interval and creatine kinase-MB in healthy people and treatment-naïve adults living with HIV-1 treated with ainuovirine monotherapy or combined with lamivudine and tenofovir DF. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhou Z – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Yun X – PersonEntity: Name: NameFull: Wu H – PersonEntity: Name: NameFull: Qin H – PersonEntity: Name: NameFull: Su B IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1879-0720 Numbering: – Type: volume Value: 222 Titles: – TitleFull: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Type: main |
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