View in EDS

Optimizing mouse models for mRNA vaccines: addressing dose translation challenges.

Saved in:
Bibliographic Details
Title: Optimizing mouse models for mRNA vaccines: addressing dose translation challenges.
Authors: Chang ZW; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan YJ; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Liao Y; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore., Goh YS; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Kabir SR; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Wang Y; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore., Hor PX; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Loh CY; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Huang Y; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wang B; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Salleh SNM; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ngoh EZX; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wang CI; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lye DC; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Communicable Diseases Agency, Singapore, Singapore., Young BE; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore., Tay MZ; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ng LFP; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ejima K; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore., Renia L; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. LCSRENIA@ntu.edu.sg.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore. LCSRENIA@ntu.edu.sg.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. LCSRENIA@ntu.edu.sg.; National Centre for Infectious Diseases, Singapore, Singapore. LCSRENIA@ntu.edu.sg.
Corporate Authors: COVID-19 Cohort Study Group, NCID Study Group, COVID-19 Clinicians’ Group
Source: Scientific reports [Sci Rep] 2026 May 05. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42086626
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Optimizing mouse models for mRNA vaccines: addressing dose translation challenges.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Chang+ZW%22">Chang ZW</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+YJ%22">Tan YJ</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liao+Y%22">Liao Y</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+YS%22">Goh YS</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kabir+SR%22">Kabir SR</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.<br /><searchLink fieldCode="AU" term="%22Hor+PX%22">Hor PX</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Loh+CY%22">Loh CY</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Salleh+SNM%22">Salleh SNM</searchLink>; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ngoh+EZX%22">Ngoh EZX</searchLink>; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+CI%22">Wang CI</searchLink>; A*STAR Singapore Immunology Network (A*STAR SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lye+DC%22">Lye DC</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Communicable Diseases Agency, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Young+BE%22">Young BE</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tay+MZ%22">Tay MZ</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ng+LFP%22">Ng LFP</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ejima+K%22">Ejima K</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Renia+L%22">Renia L</searchLink>; A*STAR Infectious Diseases Labs (A*STAR IDL), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. LCSRENIA@ntu.edu.sg.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Level 12, Singapore, 308232, Singapore. LCSRENIA@ntu.edu.sg.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. LCSRENIA@ntu.edu.sg.; National Centre for Infectious Diseases, Singapore, Singapore. LCSRENIA@ntu.edu.sg.
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22COVID-19+Cohort+Study+Group%22">COVID-19 Cohort Study Group</searchLink><br /><searchLink fieldCode="CA" term="%22NCID+Study+Group%22">NCID Study Group</searchLink><br /><searchLink fieldCode="CA" term="%22COVID-19+Clinicians%27+Group%22">COVID-19 Clinicians’ Group</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 May 05. <i>Date of Electronic Publication: </i>2026 May 05.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42086626
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41598-026-47820-z
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Optimizing mouse models for mRNA vaccines: addressing dose translation challenges.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chang ZW
      – PersonEntity:
          Name:
            NameFull: Tan YJ
      – PersonEntity:
          Name:
            NameFull: Liao Y
      – PersonEntity:
          Name:
            NameFull: Goh YS
      – PersonEntity:
          Name:
            NameFull: Kabir SR
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Hor PX
      – PersonEntity:
          Name:
            NameFull: Loh CY
      – PersonEntity:
          Name:
            NameFull: Huang Y
      – PersonEntity:
          Name:
            NameFull: Wang B
      – PersonEntity:
          Name:
            NameFull: Salleh SNM
      – PersonEntity:
          Name:
            NameFull: Ngoh EZX
      – PersonEntity:
          Name:
            NameFull: Wang CI
      – PersonEntity:
          Name:
            NameFull: Lye DC
      – PersonEntity:
          Name:
            NameFull: Young BE
      – PersonEntity:
          Name:
            NameFull: Tay MZ
      – PersonEntity:
          Name:
            NameFull: Ng LFP
      – PersonEntity:
          Name:
            NameFull: Ejima K
      – PersonEntity:
          Name:
            NameFull: Renia L
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 05
              M: 05
              Text: 2026 May 05
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2045-2322
          Titles:
            – TitleFull: Scientific reports
              Type: main
ResultId 1