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Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals.

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Title: Multinational validation of the PREVENT and SCORE2 cardiovascular risk equations across 6.4 million individuals.
Authors: Neuen BL; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.; Department of Renal Medicine, Royal North Shore Hospital, Sydney, New South Wales, Australia., Major RW; School of Medical Sciences - Public Health and Epidemiology Division (SAPPHIRE Group) College of Life Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Leicester, Leicestershire and Rutland Integrated Care Board, Leicester, UK., Grams ME; Division of Precision Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA. ckdpc@nyulangone.org., Sang Y; Optimal Aging Institute, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA., Coresh J; Optimal Aging Institute, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA. josef.coresh@nyulangone.org., Ballew SH; Optimal Aging Institute, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA., Surapaneni A; Division of Precision Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Alencar de Pinho N; Centre for Research in Epidemiology and Population Health (CESP), Clinical Epidemiology and Pharmacoepidemiology Team, Inserm U1018, Paris-Saclay University, Villejuif, France., Ärnlöv J; Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institute, Stockholm, Sweden., Arnott C; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.; Department of Cardiology, St. Vincent's Hospital, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia., Bell S; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK.; Division of Population and Behavioural Sciences, School of Medicine, University of St Andrews, St Andrews, UK., Berry J; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA., Brenner H; Cancer Prevention Graduate School, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany., Ciemins E; American Medical Group Association, Alexandria, VA, USA., Chang AR; Department of Nephrology, Geisinger Medical Center, Danville, PA, USA., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., de Lemos JA; Division of Cardiology, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX, USA., Diaz-Tocados JM; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), RICORS 2024, Lleida, Spain., Farjat AE; Clinical Statistics & Analytics, Bayer BV, Hoofddorp, The Netherlands., Fletcher RA; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.; Department of Renal Medicine, Royal North Shore Hospital, Sydney, New South Wales, Australia.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Gansevoort RT; University Medical Centre Groningen, Groningen, The Netherlands., Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, The Netherlands., Herrington WG; Renal Studies Group, Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Oxford Kidney Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Hong C; Department of Biostatistics & Bioinformatics, Duke University School of Medicine, Durham, NC, USA., Horwitz EJ; Department of Medicine, Division of Nephrology & Hypertension, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Hwang SJ; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Jassal SK; VA San Diego Healthcare System and Division of General Internal Medicine, Department of Medicine, University of California, San Diego, San Diego, CA, USA.; VA San Diego Healthcare System, San Diego, CA, USA., Kalra PA; Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK., Katz R; Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, USA., Khan SS; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Kovesdy CP; The University of Tennessee Health Science Center College of Medicine, Memphis, TN, USA.; Memphis VA Medical Center, Memphis, TN, USA., Kronenberg F; Department of Genetics, Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria., Lees JS; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK., Lloyd-Jones DM; Framingham Center for Population and Prevention Science and Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Mill JG; Department of Physiological Sciences and Cassiano Antonio Moraes University Hospital (Hucam/Ebserh), Federal University of Espírito Santo, Vitória, Brazil., Naimark DMJ; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Ndumele C; Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Baltimore, MD, USA.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD, USA., Polkinghorne KR; Department of Nephrology, Monash Medical Centre, Monash Health, Melbourne, Victoria, Australia.; Department of Medicine, Monash University, Melbourne, Victoria, Australia.; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA., Schloemer P; Clinical Statistics & Analytics, Pharmaceuticals, Bayer AG, Berlin, Germany., Shlipak MG; Kidney Health Research Collaborative, San Francisco Veterans Affairs Health Care System, University of California, San Francisco, San Francisco, CA, USA., Shrestha P; The University of Tennessee Health Science Center College of Medicine, Memphis, TN, USA., Song Z; Department of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya, Japan., Staplin N; Renal Studies Group, Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Steubl D; Boehringer Ingelheim International GmbH, Ingelheim, Germany.; Department of Nephrology, Hospital rechts der Isar, Technical University Munich, Munich, Germany., Vart P; Department of Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, The Netherlands., Visseren FLJ; Department of Vascular Medicine, Utrecht University, Utrecht, The Netherlands., Woodward M; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.; The George Institute for Global Health, School of Public Health, Imperial College London, London, UK., Yamagishi K; Department of Public Health Medicine, Institute of Medicine, and Health Services Research and Development Center, University of Tsukuba, Tsukuba, Japan.; Department of Public Health, Graduate School of Medicine, Juntendo University, Tokyo, Japan., Young BA; UW JEDI Center for Transformational Research, Office of Healthcare Equity, and Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA, USA., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore and Duke-NUS Medical School, Singapore, Singapore., Valdivielso JM; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), RICORS 2024, Lleida, Spain.
Corporate Authors: CKD Prognosis Consortium investigators
Source: Nature medicine [Nat Med] 2026 May 05. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore and Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Valdivielso+JM%22">Valdivielso JM</searchLink>; Vascular and Renal Translational Research Group, Biomedical Research Institute of Lleida, Dr. Pifarré Foundation (IRBLleida), RICORS 2024, Lleida, Spain.
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            NameFull: Song Z
      – PersonEntity:
          Name:
            NameFull: Staplin N
      – PersonEntity:
          Name:
            NameFull: Steubl D
      – PersonEntity:
          Name:
            NameFull: Vart P
      – PersonEntity:
          Name:
            NameFull: Visseren FLJ
      – PersonEntity:
          Name:
            NameFull: Woodward M
      – PersonEntity:
          Name:
            NameFull: Yamagishi K
      – PersonEntity:
          Name:
            NameFull: Young BA
      – PersonEntity:
          Name:
            NameFull: Sabanayagam C
      – PersonEntity:
          Name:
            NameFull: Valdivielso JM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 05
              M: 05
              Text: 2026 May 05
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1546-170X
          Titles:
            – TitleFull: Nature medicine
              Type: main
ResultId 1