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Biomarker-based clustering identifies distinct pulmonary function trajectories in early systemic sclerosis.

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Title: Biomarker-based clustering identifies distinct pulmonary function trajectories in early systemic sclerosis.
Authors: Uesugi-Uchida S; Department of Dermatology, University of Fukui, Fukui, Japan., Asano Y; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan., Endo H; Department of Rheumatology, Southern Tohoku General Hospital, Fukushima, Japan., Goto D; Division of Rheumatology, Ibaraki Prefectural Central Hospital and Cancer Center, Ibaraki, Japan., Jinnin M; Department of Dermatology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan., Kawaguchi Y; Division of Rheumatology, Department of Internal Medicine, Tokyo Women's Medical University, Tokyo, Japan., Koike Y; Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kuwana M; Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan., Tanaka S; Department of Rheumatology, Kitasato University Medical Center, Kitamoto, Japan., Makino K; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Matsushita T; Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan., Motegi SI; Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan., Sumida H; Department of Dermatology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan., Ueda-Hayakawa I; Department of Dermatology, The University of Osaka Graduate School of Medicine, Suita, Japan., Toyama T; Department of Nephrology, University of Fukui, Fukui, Japan., Hasegawa M; Department of Dermatology, University of Fukui, Fukui, Japan.
Source: Frontiers in immunology [Front Immunol] 2026 Apr 20; Vol. 17, pp. 1798420. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Uesugi-Uchida+S%22">Uesugi-Uchida S</searchLink>; Department of Dermatology, University of Fukui, Fukui, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+Y%22">Asano Y</searchLink>; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Endo+H%22">Endo H</searchLink>; Department of Rheumatology, Southern Tohoku General Hospital, Fukushima, Japan.<br /><searchLink fieldCode="AU" term="%22Goto+D%22">Goto D</searchLink>; Division of Rheumatology, Ibaraki Prefectural Central Hospital and Cancer Center, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22Jinnin+M%22">Jinnin M</searchLink>; Department of Dermatology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Kawaguchi+Y%22">Kawaguchi Y</searchLink>; Division of Rheumatology, Department of Internal Medicine, Tokyo Women's Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Koike+Y%22">Koike Y</searchLink>; Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kuwana+M%22">Kuwana M</searchLink>; Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+S%22">Tanaka S</searchLink>; Department of Rheumatology, Kitasato University Medical Center, Kitamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Makino+K%22">Makino K</searchLink>; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Matsushita+T%22">Matsushita T</searchLink>; Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Motegi+SI%22">Motegi SI</searchLink>; Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan.<br /><searchLink fieldCode="AU" term="%22Sumida+H%22">Sumida H</searchLink>; Department of Dermatology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ueda-Hayakawa+I%22">Ueda-Hayakawa I</searchLink>; Department of Dermatology, The University of Osaka Graduate School of Medicine, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Toyama+T%22">Toyama T</searchLink>; Department of Nephrology, University of Fukui, Fukui, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+M%22">Hasegawa M</searchLink>; Department of Dermatology, University of Fukui, Fukui, Japan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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