Probiotic-conditioned microbiota from preterm infants modulate immune response to pathogen challenge in a microbiota-humanized mouse model.
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| Title: | Probiotic-conditioned microbiota from preterm infants modulate immune response to pathogen challenge in a microbiota-humanized mouse model. |
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| Authors: | Smout J; Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Lesker TR; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany., Hoenicke L; Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Ortiz D; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany., Zou M; Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Kruse F; Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Pirr S; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.; Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany., Willers M; Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany., Härtel C; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany., Falk C; Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner site Hannover-Braunschweig, Hannover, Germany., Torow N; Junior Research Group Early Life Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Viemann D; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany.; Center for Infection Research, University Würzburg, Würzburg, Germany., Strowig T; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany.; Center for Individualized Infection Medicine (CiiM), a joint venture of Hannover Medical School and Helmholtz Centre for Infection Research, Hannover, Germany., Huehn J; Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Apr 20; Vol. 17, pp. 1761680. Date of Electronic Publication: 2026 Apr 20 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1761680 |