VRC01 with antiretroviral initiation in infants is well tolerated, and higher concentrations associate with greater HIV-1 DNA declines.
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| Title: | VRC01 with antiretroviral initiation in infants is well tolerated, and higher concentrations associate with greater HIV-1 DNA declines. |
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| Authors: | Khaitan A; Indiana University School of Medicine, Indianapolis, IN 46202, USA., Lindsey JC; Center for Biostatistics in AIDS Research, Harvard TH Chan School of Public Health, Boston, MA 02115, USA., Capparelli EV; University of California, San Diego, San Diego, CA 92093, USA., Tierney C; Center for Biostatistics in AIDS Research, Harvard TH Chan School of Public Health, Boston, MA 02115, USA., Coletti A; IMPAACT Operations Center, FHI 360, Durham, NC 27701, USA., Perlowski C; IMPAACT Operations Center, FHI 360, Durham, NC 27701, USA., Yin DE; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA., Smith MEB; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA., Spiegel HML; Kelly Government Solutions, Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA., Majji S; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Maternal and Pediatric Infectious Disease Branch, Bethesda, MD 20817, USA., Moye J; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Maternal and Pediatric Infectious Disease Branch, Bethesda, MD 20817, USA., Gama L; Vaccine Research Center, Bethesda, MD 20814, USA., Koup RA; Vaccine Research Center, Bethesda, MD 20814, USA., Lin BC; Vaccine Research Center, Bethesda, MD 20814, USA., McDermott AB; Vaccine Research Center, Bethesda, MD 20814, USA., Purdue L; Kelly Government Solutions, Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA., Krotje C; Frontier Science Foundation, Amherst, NY 14226, USA., Harding PA; University of Colorado Anschutz School of Medicine, Denver, CO 80045, USA., Cotton MF; Family Centre for Research with Ubuntu (FAMCRU), Stellenbosch University, Stellenbosch 7505, South Africa., Costello D; MacDonald Research Laboratory, University of California at Los Angeles, Los Angeles, CA 90095, USA., Petropoulos CJ; Labcorp-Monogram Biosciences, South San Francisco, CA 94080, USA., Reeves JD; Labcorp-Monogram Biosciences, South San Francisco, CA 94080, USA., Mallewa M; Kamuzu University of Health Sciences-Johns Hopkins Research Project, Blantyre 312223, Malawi., Chihana R; Kamuzu University of Health Sciences-Johns Hopkins Research Project, Blantyre 312223, Malawi., Kamthunzi P; UNC Malawi CRS, Lilongwe 207233, Malawi., Mbengeranwa TG; Clinical Trials Research Centre, University of Zimbabwe, Harare Zimbabwe., Masheto G; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana., Santos Cruz ML; Hospital Federal dos Servidores do Estado, Rio de Janeiro, RJ 20221-903, Brazil., Pilotto JH; Hospital Geral de Nova Iguaçu & Laboratório de Aids e Imunologia Molecular/IOC, Nova Iguaçu, RJ 26030-380, Brazil., Ponatshego PL; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana., Persaud D; Johns Hopkins University, Baltimore, MD 21205, USA., McFarland EJ; University of Colorado Anschutz School of Medicine, Denver, CO 80045, USA. |
| Corporate Authors: | IMPAACT 2008 Team |
| Source: | Science translational medicine [Sci Transl Med] 2026 May 06; Vol. 18 (848), pp. eadr4509. Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.adr4509 |