Enabling DCIS subtyping: leveraging foundation models for robust grading and molecular biomarker scoring.

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Title: Enabling DCIS subtyping: leveraging foundation models for robust grading and molecular biomarker scoring.
Authors: Doyle S; Division of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Informatics Institute, University of Amsterdam, Amsterdam, the Netherlands., Oerlemans MA; Division of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Brunekreef J; Division of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Informatics Institute, University of Amsterdam, Amsterdam, the Netherlands., Marcus E; Division of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Informatics Institute, University of Amsterdam, Amsterdam, the Netherlands., Mulder L; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Liu Y; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Bouybayoune I; School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Sawyer EJ; School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Thompson AM; Department of Surgery, Baylor College of Medicine, Houston, TX, USA., Pinder SE; School of Cancer & Pharmaceutical Sciences, King's College London, London, UK., Wesseling J; Netherlands Cancer Institute, Amsterdam, the Netherlands., Thompson A; Baylor College of Medicine, Houston, TX, USA., Nik-Zainal S; University of Cambridge, Cambridge, UK., Sawyer EJ; King's College London, London, UK., Davies H; University of Cambridge, Cambridge, UK., Futreal A; MD Anderson Cancer Center, Houston, TX, USA., Navin N; MD Anderson Cancer Center, Houston, TX, USA., Hwang ES; Duke University School of Medicine, Durham, NC, USA., Jonkers J; Netherlands Cancer Institute, Amsterdam, the Netherlands., van Rheenen J; Netherlands Cancer Institute, Amsterdam, the Netherlands., Behbod F; Kansas University Medical Center, Kansas City, KS, USA., Lips EH; Netherlands Cancer Institute, Amsterdam, the Netherlands., Schmidt M; Netherlands Cancer Institute, Amsterdam, the Netherlands., Wessels LFA; Netherlands Cancer Institute, Amsterdam, the Netherlands., Rea D; University of Birmingham, Birmingham, UK., Bhattacharjee P; Netherlands Cancer Institute, Amsterdam, the Netherlands., Stobart H; Independent Cancer Patients' Voice, London, UK., Collyar D; Patient Advocates in Research, New York, NY, USA., Pinto D; DCIS411, Houston, TX, USA., Verschuur E; Borstkanker Vereniging Nederland, Utrecht, the Netherlands., van Oirsouw M; Borstkanker Vereniging Nederland, Utrecht, the Netherlands., Sánchez CI; Informatics Institute, University of Amsterdam, Amsterdam, the Netherlands., Teuwen J; Division of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Imaging, Radboud University Nijmegen, Nijmegen, the Netherlands., Wesseling J; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Lips EH; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands. e.lips@nki.nl.
Corporate Authors: Grand Challenge PRECISION Consortium
Source: NPJ breast cancer [NPJ Breast Cancer] 2026 May 06. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article
Journal Info: Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer
Database: MEDLINE Ultimate
Description
ISSN:2374-4677
DOI:10.1038/s41523-026-00957-6