Disrupted molecular glue complex drives RAS inhibitor resistance.

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Bibliographic Details
Title: Disrupted molecular glue complex drives RAS inhibitor resistance.
Authors: Sang B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ye LF; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fu Z; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pourfarjam Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cuevas-Navarro A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fan S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hu F; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Washington A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rodriguez DJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Tri-Institutional MD-PhD Program, Weill Cornell Medical College, Rockefeller University, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vides A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kar S; Revolution Medicines, Redwood City, CA, USA., Ahler E; Revolution Medicines, Redwood City, CA, USA., Lin KK; Revolution Medicines, Redwood City, CA, USA., Hegde A; Revolution Medicines, Redwood City, CA, USA., Smith JAM; Revolution Medicines, Redwood City, CA, USA., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Punekar SR; Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA., Spira AI; Virginia Cancer Specialists Research Institute, Fairfax, VA, USA., Garrido-Laguna I; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Hong DS; Department of Investigational Cancer Therapeutics, MD Anderson Cancer Center, Houston, TX, USA., Dar AC; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yaeger R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Arbour KC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Lito P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Tri-Institutional MD-PhD Program, Weill Cornell Medical College, Rockefeller University, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. Electronic address: litop@mskcc.org.
Source: Cell [Cell] 2026 May 14; Vol. 189 (10), pp. 2918-2933.e17. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4172
DOI:10.1016/j.cell.2026.03.031