Small molecules targeting the PD-1/PD-L1 axis for cancer immunotherapy.

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Title: Small molecules targeting the PD-1/PD-L1 axis for cancer immunotherapy.
Authors: Yin JY; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu HM; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Li SL; Department of Orthopaedics, Qilu Hospital, Shandong University Centre for Orthopaedics, Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Shandong, 250012, China., Ji XQ; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Wang JJ; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Fu MJ; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu CJ; School of Food and Health Engineering, Zhengzhou University of Technology, Zhengzhou 450000, China., Wang N; School of Chinese Medicine, University of Hong Kong, 3, Sasson Road, Pokfulam, Hong Kong., Lu GL; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.; Maurice Wilkins Centre, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand., Li Y; Maurice Wilkins Centre, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.; Department of Biomedicine and Medical Diagnostics, School of Science, Auckland University of Technology. 34 St. Paul Street, Auckland 1010, New Zealand., Liu HM; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Zheng YC; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Dai XJ; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, China; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer; Key Laboratory of Henan Province for Drug Quality and Evaluation; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu Y; Department of Pharmacy, Henan Province Engineering Research Center of Application & Translation of Precision Clinical Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Source: Theranostics [Theranostics] 2026 Apr 08; Vol. 16 (11), pp. 6051-6080. Date of Electronic Publication: 2026 Apr 08 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1838-7640
DOI:10.7150/thno.130935