How PPMI Enabled the First Interventional Platform Trial to Test Therapies in Participants With Early-Stage Neuronal Alpha-Synuclein Disease.

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Bibliographic Details
Title: How PPMI Enabled the First Interventional Platform Trial to Test Therapies in Participants With Early-Stage Neuronal Alpha-Synuclein Disease.
Authors: Simuni T; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL., Coffey CS; Department of Biostatistics, University of Iowa, Iowa City, IA., Kopil CM; The Michael J. Fox Foundation for Parkinson's Research, New York, NY., Allen-Savietta C; Berry Consultants, LLC, Austin, TX., Wendelberger B; Berry Consultants, LLC, Austin, TX., Crawford A; Berry Consultants, LLC, Austin, TX., Schneider RB; Department of Neurology, University of Rochester, Rochester, NY., Siderowf A; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Kieburtz K; Department of Neurology, University of Rochester, Rochester, NY., Tanner CM; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA., Tropea TF; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Institute for Neurodegenerative Disorders, New Haven, CT., Whalen H; Institute for Neurodegenerative Disorders, New Haven, CT., Ramia L; Institute for Neurodegenerative Disorders, New Haven, CT., Kamp C; Department of Neurology, University of Rochester, Rochester, NY., Reyes C; Institute for Neurodegenerative Disorders, New Haven, CT., Fabrizio K; Institute for Neurodegenerative Disorders, New Haven, CT., Willson T; The Michael J. Fox Foundation for Parkinson's Research, New York, NY., Merriam E; Institute for Neurodegenerative Disorders, New Haven, CT., Kuhl MM; The Michael J. Fox Foundation for Parkinson's Research, New York, NY., Chowdhury S; The Michael J. Fox Foundation for Parkinson's Research, New York, NY., Marek K; Institute for Neurodegenerative Disorders, New Haven, CT.
Corporate Authors: Parkinson's Progression Markers Initiative
Source: Annals of neurology [Ann Neurol] 2026 May 07. Date of Electronic Publication: 2026 May 07.
Publication Type: Editorial
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1531-8249
DOI:10.1002/ana.78250