Lysosomal function, resistance to oxidative stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant.
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| Title: | Lysosomal function, resistance to oxidative stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant. |
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| Authors: | Hernández-Gerez E; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Goya-Iglesias N; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Viedma-Poyatos Á; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Pajares MA; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Pérez-Sala D; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain. Electronic address: dperezsala@cib.csic.es. |
| Source: | Free radical biology & medicine [Free Radic Biol Med] 2026 Aug 16; Vol. 252, pp. 295-310. Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1873-4596 |
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| DOI: | 10.1016/j.freeradbiomed.2026.05.280 |