Lysosomal function, resistance to oxidative stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant.

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Bibliographic Details
Title: Lysosomal function, resistance to oxidative stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant.
Authors: Hernández-Gerez E; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Goya-Iglesias N; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Viedma-Poyatos Á; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Pajares MA; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain., Pérez-Sala D; Department of Molecular and Cellular Biosciences, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Spain. Electronic address: dperezsala@cib.csic.es.
Source: Free radical biology & medicine [Free Radic Biol Med] 2026 Aug 16; Vol. 252, pp. 295-310. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4596
DOI:10.1016/j.freeradbiomed.2026.05.280