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The contribution of rare germline variants to the immune landscape of breast cancer.

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Title: The contribution of rare germline variants to the immune landscape of breast cancer.
Authors: Rojas-Rodríguez F; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands., Canisius S; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands.; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands., Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands., Bernstein AJ; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK.; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.; Office of Drug Development Partnership Programs (ODDPP), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Bethesda, MD, 20817, USA., Hurson AN; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Ahearn TU; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Andrulis IL; Fred A. Litwin Center for Cancer Genetics Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital Toronto, Toronto, ON, M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Antoniou AC; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Białkowska K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, 71-252, Poland., Blows FM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Bolla MK; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Camp NJ; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Cessna MH; Department of Pathology and Intermountain Biorepository, Intermountain Health, Murray, UT, 84123, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Dennis J; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, 2333 ZA, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, 2333 ZA, the Netherlands., Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, 71-252, Poland., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, 3015 GD, the Netherlands., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, 3015 GD, the Netherlands., Horlings HM; Department of Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands., Jager A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, 3015 GD, the Netherlands., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, 71-252, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, 171-252, Poland., Jones B; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Kok M; Department of Medical Oncology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands.; Department of Tumor Biology and Immunology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands., Lissowska J; Department of Cancer Epidemiology and Prevention, M Sklodowska-Curie National Research Oncology Institute, Warsaw, 02-034, Poland., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, 71-252, Poland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany., Miller JL; Histopathology/ISH Core Facility, Cancer Research, UK Cambridge Institute, University of Cambridge, Cambridge, CB2 0RE, UK., Muhammad N; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, 54000, Pakistan., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, M5G 2C4, Canada., Obi N; Institute for Occupational and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.; Institute for Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany., Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, 54000, Pakistan., Sinn HP; Institute of Pathology, Heidelberg University Hospital, Heidelberg, 69120, Germany., van Deurzen CHM; Department of Pathology, Erasmus University Medical Center, Rotterdam, 3015 CN, the Netherlands., Wang Q; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Williams JA; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Yang XR; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Easton DF; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK.; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK., Ali HR; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 0RE, UK., García-Closas M; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK., Pharoah PDP; Department of Computational Biomedicine, Cedars-Sinai Health Sciences University, West Hollywood, CA, 90069, USA., Abubakar M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands. mk.schmidt@nki.nl.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands. mk.schmidt@nki.nl.; Department of Clinical Genetics, Leiden University Medical Center, Leiden, 2333 ZA, the Netherlands. mk.schmidt@nki.nl.
Source: Genome medicine [Genome Med] 2026 May 09. Date of Electronic Publication: 2026 May 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The contribution of rare germline variants to the immune landscape of breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Rojas-Rodríguez+F%22">Rojas-Rodríguez F</searchLink>; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Canisius+S%22">Canisius S</searchLink>; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands.; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Keeman+R%22">Keeman R</searchLink>; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bernstein+AJ%22">Bernstein AJ</searchLink>; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK.; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.; Office of Drug Development Partnership Programs (ODDPP), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Bethesda, MD, 20817, USA.<br /><searchLink fieldCode="AU" term="%22Hurson+AN%22">Hurson AN</searchLink>; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Ahearn+TU%22">Ahearn TU</searchLink>; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Andrulis+IL%22">Andrulis IL</searchLink>; Fred A. 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Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB1 8RN, UK.<br /><searchLink fieldCode="AU" term="%22Camp+NJ%22">Camp NJ</searchLink>; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA.<br /><searchLink fieldCode="AU" term="%22Cessna+MH%22">Cessna MH</searchLink>; Department of Pathology and Intermountain Biorepository, Intermountain Health, Murray, UT, 84123, USA.<br /><searchLink fieldCode="AU" term="%22Chang-Claude+J%22">Chang-Claude J</searchLink>; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.<br /><searchLink fieldCode="AU" term="%22Chanock+SJ%22">Chanock SJ</searchLink>; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Dennis+J%22">Dennis J</searchLink>; 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Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+MK%22">Schmidt MK</searchLink>; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands. mk.schmidt@nki.nl.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, the Netherlands. mk.schmidt@nki.nl.; Department of Clinical Genetics, Leiden University Medical Center, Leiden, 2333 ZA, the Netherlands. mk.schmidt@nki.nl.
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            NameFull: Abubakar M
      – PersonEntity:
          Name:
            NameFull: Schmidt MK
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 09
              M: 05
              Text: 2026 May 09
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1756-994X
          Titles:
            – TitleFull: Genome medicine
              Type: main
ResultId 1