Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project.

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Title: Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project.
Authors: Yang X; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK., Usher-Smith JA; Primary Care Unit, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK., Blackmore KM; Ontario Health, Toronto, ON M5G 2L3, Canada., Brooks JD; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5S 1A1, Canada., Bell KA; Ontario Health, Toronto, ON M5G 2L3, Canada., Carver T; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK., Chang A; Ontario Health, Toronto, ON M5G 2L3, Canada., Chiquette J; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.; Department of Family Medicine and Emergency Medicine, Faculty of Medicine, Université Laval, Quebec City, QC G1V 0A6, Canada., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Eisen A; Ontario Health, Toronto, ON M5G 2L3, Canada.; Sunnybrook Health Science Centre, Toronto, ON M4N 3M5, Canada.; Department of Oncology, McMaster University, Hamilton, ON L8V 5C2, Canada., Eloy L; Programme Québécois de Cancérologie, Ministère de la Santé et des Services Sociaux, Quebec City, QC G1S 2M1, Canada.; Centre Intégré de Santé et de Services Sociaux de Lanaudière, Centre hospitalier de Lanaudière, Saint-Charles Borromée, QC J6E 6J2, Canada., Fienberg S; Ontario Health, Toronto, ON M5G 2L3, Canada., Joly Y; Centre of Genomics and Policy, McGill University, Montreal, QC H3A 0G1, Canada., Kim RH; Ontario Health, Toronto, ON M5G 2L3, Canada.; Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada., Knoppers BM; Centre of Genomics and Policy, McGill University, Montreal, QC H3A 0G1, Canada., Lambert-Côté L; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada., Nabi H; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.; Department of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Quebec City, QC G1V 0A6, Canada.; Université Laval Cancer Research Center, Quebec City, QC G1R 3S3, Canada., Pashayan N; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK., Soucy P; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada., Stockley TL; Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.; Division of Clinical Laboratory Genetics, University Health Network, Toronto, ON M5G 2C4, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., Turgeon A; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada., Walker MJ; Ontario Health, Toronto, ON M5G 2L3, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5S 1A1, Canada., Wolfson M; School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1G 5Z3, Canada., Dorval M; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.; Université Laval Cancer Research Center, Quebec City, QC G1R 3S3, Canada.; Faculty of Pharmacy, Université Laval, Quebec City, QC G1V 0A6, Canada., Chiarelli AM; Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5S 1A1, Canada., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK., Simard J; CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.; Université Laval Cancer Research Center, Quebec City, QC G1R 3S3, Canada.; Department of Molecular Medicine, Faculty of Medicine, Université Laval, Quebec City, QC G1V 4G2, Canada.
Source: Cancers [Cancers (Basel)] 2026 May 05; Vol. 18 (9). Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2072-6694
DOI:10.3390/cancers18091482