Organoid models reveal mechanistic connections and sirolimus efficacy in liver-vascular steatosis and foam cell formation.

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Bibliographic Details
Title: Organoid models reveal mechanistic connections and sirolimus efficacy in liver-vascular steatosis and foam cell formation.
Authors: Kota VG; NUS Biomedical Engineering, College of Design and Engineering, National University of Singapore, 4 Engineering Drive 3 Block 4, #04-08, 117583, Singapore. Electronic address: e1100036@u.nus.edu., Yi JLJ; NUS Biomedical Engineering, College of Design and Engineering, National University of Singapore, 4 Engineering Drive 3 Block 4, #04-08, 117583, Singapore., Zhang Z; Department of Physiology, The Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, MD9-04-11, 2 Medical Drive, Singapore, 117593, Singapore., Yooyuen A; NUS Biomedical Engineering, College of Design and Engineering, National University of Singapore, 4 Engineering Drive 3 Block 4, #04-08, 117583, Singapore., Yu H; Department of Physiology, The Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, MD9-04-11, 2 Medical Drive, Singapore, 117593, Singapore; Mechanobiology Institute, National University of Singapore, T-Lab, #05-01, 5A Engineering Drive 1, Singapore, 117411, Singapore; CAMP, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, Level 4 Enterprise Wing, Singapore, 138602, Singapore., Leo HL; NUS Biomedical Engineering, College of Design and Engineering, National University of Singapore, 4 Engineering Drive 3 Block 4, #04-08, 117583, Singapore.
Source: Atherosclerosis [Atherosclerosis] 2026 Jun; Vol. 417, pp. 120762. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-1484
DOI:10.1016/j.atherosclerosis.2026.120762