Superparamagnetic iron oxide nanoparticle-driven 3-aroyl-1,4-diarylpyrrole nanocomposites (ARDAP@SPION-PEI) mediate renal cancer cell PANoptosis by regulating chromatin accessibility.
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| Title: | Superparamagnetic iron oxide nanoparticle-driven 3-aroyl-1,4-diarylpyrrole nanocomposites (ARDAP@SPION-PEI) mediate renal cancer cell PANoptosis by regulating chromatin accessibility. |
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| Authors: | Shen H; Department of Urology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Beijing, 100050, China. shenhl2004@163.com.; Institute of Urology, Beijing Municipal Health Commission, Beijing, 100050, China. shenhl2004@163.com., Cui Z; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365 South Xiangyang Road, Shanghai, 200031, China., Wu Y; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China., Puxeddu M; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Lai Y; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365 South Xiangyang Road, Shanghai, 200031, China., Mo R; Department of Urology, Inner Mongolia People's Hospital, Inner Mongolia Urological Institute, Hohhot, Inner Mongolia, 010017, China., Yang B; Department of Urology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Beijing, 100050, China.; Institute of Urology, Beijing Municipal Health Commission, Beijing, 100050, China., Niu Y; Department of Urology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Beijing, 100050, China.; Institute of Urology, Beijing Municipal Health Commission, Beijing, 100050, China., Wen Y; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365 South Xiangyang Road, Shanghai, 200031, China., Du X; School of Life Science and Technology, Tongji University, Shanghai, 200092, China., Silvestri R; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. romano.silvestri@uniroma1.it., Liu T; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365 South Xiangyang Road, Shanghai, 200031, China. liute1979@shutcm.edu.cn. |
| Source: | Molecular biomedicine [Mol Biomed] 2026 May 15; Vol. 7 (1). Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2662-8651 |
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| DOI: | 10.1186/s43556-026-00470-z |
