The role of whole genome sequencing in antimicrobial susceptibility prediction of bacteria: 2025 update from the European Committee on Antimicrobial Susceptibility Testing Subcommittee.

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Title: The role of whole genome sequencing in antimicrobial susceptibility prediction of bacteria: 2025 update from the European Committee on Antimicrobial Susceptibility Testing Subcommittee.
Authors: Samuelsen Ø; Norwegian Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway; Department of Pharmacy, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway. Electronic address: orjan.samuelsen@unn.no., López-Causapé C; Servicio de Microbiología, Hospital Son Espases, IdISBa, Palma de Mallorca, Spain; CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain., Aarestrup FM; Research Group for Genomic Epidemiology, National Food Institute, Technical University of Denmark, Lyngby, Denmark., Bortolaia V; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark., Brouwer MSM; Wageningen Bioveterinary Research, Part of Wageningen University and Research, Lelystad, The Netherlands; Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Cantón R; CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain; Servicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Egli A; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Grad YH; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA., Hamprecht A; Institute of Medical Microbiology and Virology, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany., Haussler S; Department of Molecular Bacteriology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany; Institute of Molecular Bacteriology, TWINCORE Centre for Experimental and Clinical Infection Research, a Joint Venture of the Hannover Medical School (MHH) and the HZI, Hannover, Germany; Department of Clinical Microbiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Holt KE; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK; Department of Infectious Diseases, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia., Hopkins KL; Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit. 2, AMR & HCAI Division, UK Health Security Agency, London, UK., Howden BP; Microbiological Diagnostic Unit Public Health Laboratory, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Centre for Pathogen Genomics, The University of Melbourne, Melbourne, Victoria, Australia; Department of Infectious Diseases, Austin Health, Heidelberg, Melbourne, Victoria, Australia., Jeannot K; Laboratoire Chrono-environnement (UMR 6249), University Marie and Louis Pasteur, Laboratoire de bactériologie CHU Besançon, CNRS, Besançon, France., Kahlmeter G; EUCAST Development Laboratory, Central Hospital, Växjö, Sweden., Köser CU; Department of Genetics, University of Cambridge, Cambridge, UK; Department of Biomedical and Clinical Sciences, Division of Infection and Inflammation, Linköping University, Linköping, Sweden., Mathers AJ; Division of Infectious Diseases and Department of Pathology, School of Medicine, University of Virginia, Charlottesville, VA., Naas T; Team 'Resist', UMR1184, INSERM, Faculty of Medicine, Université Paris-Saclay, CEA, Le Kremlin-Bicêtre, France; Department of Bacteriology-Hygiene, Bicêtre Hospital, AP-HP Paris-Saclay, Le Kremlin-Bicêtre, France; French National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacterales, Le Kremlin-Bicêtre, France., Pournaras S; Laboratory of Clinical Microbiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Ruppé E; Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME and AP-HP, Hôpital Bichat-Claude Bernard, Laboratoire de Bactériologie, Paris, France., Schön T; Department of Biomedical and Clinical Sciences, Division of Infection and Inflammation, Linköping University, Linköping, Sweden; Department of Infectious Diseases, Kalmar County Hospital, Linköping University, Kalmar, Sweden; Department of Infectious Diseases, Linköping University Hospital, Linköping, Sweden., Stoesser N; Nuffield Department of Medicine, University of Oxford, Oxford, UK; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with UK Health Security Agency, Nuffield Department of Medicine, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK., Turnidge J; Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia., Werner G; Division of Nosocomial Pathogens and Antibiotic Resistances, Department of Infectious Diseases, Robert Koch Institute, Wernigerode Branch, Germany; National Reference Centre for Staphylococci and Enterococci, Wernigerode Branch, 38855 Wernigerode, Germany., Wright GD; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Giske CG; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden., Oliver A; Servicio de Microbiología, Hospital Son Espases, IdISBa, Palma de Mallorca, Spain; CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: antonio.oliver@ssib.es.
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2026 May 15. Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1469-0691
DOI:10.1016/j.cmi.2026.05.012