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Citrus depressa modulates endogenous aromatic amino acids to regulate the kynurenine pathway and ameliorate bleomycin-induced pulmonary fibrosis.

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Title: Citrus depressa modulates endogenous aromatic amino acids to regulate the kynurenine pathway and ameliorate bleomycin-induced pulmonary fibrosis.
Authors: Liu TW; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan. Electronic address: d301110010@tmu.edu.tw., Zhuang XY; Department of Food Science, National Chiayi University, Chiayi City, Taiwan. Electronic address: vicky960471@gmail.com., Chu MH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan. Electronic address: d301111003@tmu.edu.tw., Wang YH; Ph. D. Program in the Clinical Drug Development of Herbal Medicine, Taipei Medical University, Taipei, 11042, Taiwan. Electronic address: d339111001@tmu.edu.tw., Hsieh YSY; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Division of Glycoscience, Department of Chemistry, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, AlbaNova University Centre, Stockholm, SE106 91, Sweden. Electronic address: yvhsieh@kth.se., Hsu SJ; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Institute of Fisheries Science, National Taiwan University, Taipei City, Taiwan. Electronic address: juliashu1101@gmail.com., Iskandar B; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Department of Pharmaceutical Technology, Riau College of Pharmaceutical Sciences (STIFAR), Riau, 28292, Indonesia. Electronic address: benniiskandar@stifar-riau.ac.id., Lin SM; Department of Food Science, National Chiayi University, Chiayi City, Taiwan. Electronic address: smlin00@mail.ncyu.edu.tw., Wu HH; Department of Surgery, Tainan Municipal Hospital, Tainan, 70173, Taiwan. Electronic address: 2l1416@tmh.org.tw., Lee CK; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Ph. D. Program in the Clinical Drug Development of Herbal Medicine, Taipei Medical University, Taipei, 11042, Taiwan; Department of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan. Electronic address: cklee@tmu.edu.tw.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Oct 28; Vol. 369, pp. 121870. Date of Electronic Publication: 2026 May 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Citrus depressa modulates endogenous aromatic amino acids to regulate the kynurenine pathway and ameliorate bleomycin-induced pulmonary fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Liu+TW%22">Liu TW</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan. Electronic address: d301110010@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Zhuang+XY%22">Zhuang XY</searchLink>; Department of Food Science, National Chiayi University, Chiayi City, Taiwan. Electronic address: vicky960471@gmail.com.<br /><searchLink fieldCode="AU" term="%22Chu+MH%22">Chu MH</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan. Electronic address: d301111003@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Wang+YH%22">Wang YH</searchLink>; Ph. D. Program in the Clinical Drug Development of Herbal Medicine, Taipei Medical University, Taipei, 11042, Taiwan. Electronic address: d339111001@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Hsieh+YSY%22">Hsieh YSY</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Division of Glycoscience, Department of Chemistry, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, AlbaNova University Centre, Stockholm, SE106 91, Sweden. Electronic address: yvhsieh@kth.se.<br /><searchLink fieldCode="AU" term="%22Hsu+SJ%22">Hsu SJ</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Institute of Fisheries Science, National Taiwan University, Taipei City, Taiwan. Electronic address: juliashu1101@gmail.com.<br /><searchLink fieldCode="AU" term="%22Iskandar+B%22">Iskandar B</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Department of Pharmaceutical Technology, Riau College of Pharmaceutical Sciences (STIFAR), Riau, 28292, Indonesia. Electronic address: benniiskandar@stifar-riau.ac.id.<br /><searchLink fieldCode="AU" term="%22Lin+SM%22">Lin SM</searchLink>; Department of Food Science, National Chiayi University, Chiayi City, Taiwan. Electronic address: smlin00@mail.ncyu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Wu+HH%22">Wu HH</searchLink>; Department of Surgery, Tainan Municipal Hospital, Tainan, 70173, Taiwan. Electronic address: 2l1416@tmh.org.tw.<br /><searchLink fieldCode="AU" term="%22Lee+CK%22">Lee CK</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 11042, Taiwan; Ph. D. Program in the Clinical Drug Development of Herbal Medicine, Taipei Medical University, Taipei, 11042, Taiwan; Department of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan. Electronic address: cklee@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%227903310%22">Journal of ethnopharmacology</searchLink> [J Ethnopharmacol] 2026 Oct 28; Vol. 369, pp. 121870. <i>Date of Electronic Publication: </i>2026 May 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Sequoia%22">Elsevier Sequoia </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7903310 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7573 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203788741%22">03788741 </searchLink><i>NLM ISO Abbreviation: </i>J Ethnopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jep.2026.121870
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      – Code: eng
        Text: English
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        StartPage: 121870
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      – TitleFull: Citrus depressa modulates endogenous aromatic amino acids to regulate the kynurenine pathway and ameliorate bleomycin-induced pulmonary fibrosis.
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            – D: 28
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              Text: 2026 Oct 28
              Type: published
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