Targeting EHMT2 overcomes 5-fluorouracil resistance in colorectal cancer by modulating cell cycle and apoptosis.
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| Title: | Targeting EHMT2 overcomes 5-fluorouracil resistance in colorectal cancer by modulating cell cycle and apoptosis. |
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| Authors: | Tae IH; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Kang Y; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Lee J; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Lee JM; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Kim J; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Lee SG; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Park K; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Ryu TY; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Kim K; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Kim G; School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Son T; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Lee HW; Department of Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea., Kim S; Chungnam National University College of Medicine, Daejeon, Republic of Korea., Lee HJ; Chungnam National University College of Medicine, Daejeon, Republic of Korea., Jung CR; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Lim JH; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Lee MS; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Korea University of Science and Technology, Daejeon, Republic of Korea., Hur K; School of Medicine, Kyungpook National University, Daegu, Republic of Korea. KeunHur@knu.ac.kr., Han TS; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea. tshan@kribb.re.kr.; Korea University of Science and Technology, Daejeon, Republic of Korea. tshan@kribb.re.kr.; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea. tshan@kribb.re.kr., Kim DS; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea. kds2465@kribb.re.kr.; Korea University of Science and Technology, Daejeon, Republic of Korea. kds2465@kribb.re.kr., Son MY; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea. myson@kribb.re.kr.; Korea University of Science and Technology, Daejeon, Republic of Korea. myson@kribb.re.kr.; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea. myson@kribb.re.kr., Cho HS; Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea. chohs@kribb.re.kr.; Korea University of Science and Technology, Daejeon, Republic of Korea. chohs@kribb.re.kr.; Department of Biological Science, Sungkyunkwan University, Suwon, Republic of Korea. chohs@kribb.re.kr.; Institute for Bio Technology Convergence, Kyungpook National University, Daegu, Republic of Korea. chohs@kribb.re.kr. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 May 18; Vol. 11 (1). Date of Electronic Publication: 2026 May 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-026-02692-7 |
