Integrated pharmacology and experimental validation reveals potential multiple mechanisms of the neutrophil elastase inhibitor sivelestat in attenuating myocarditis.
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| Title: | Integrated pharmacology and experimental validation reveals potential multiple mechanisms of the neutrophil elastase inhibitor sivelestat in attenuating myocarditis. |
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| Authors: | Ren R; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.; Department of Cardiothoracic and Vascular Surgery and Critical Care Medicine, Xi'an No.1 Hospital and The First Affiliated Hospital of Northwest University, Xi'an, Shaanxi, China., Wang N; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University and Anhui Public Health Clinical Center, Hefei, Anhui, China., Chen C; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University and Anhui Public Health Clinical Center, Hefei, Anhui, China., Yang M; Cornerstone of Health Technology (Shaanxi) Co., Ltd., Xianyang, Shaanxi, China., Li B; Department of Cardiothoracic and Vascular Surgery and Critical Care Medicine, Xi'an No.1 Hospital and The First Affiliated Hospital of Northwest University, Xi'an, Shaanxi, China., Yang Y; Department of Cardiothoracic and Vascular Surgery and Critical Care Medicine, Xi'an No.1 Hospital and The First Affiliated Hospital of Northwest University, Xi'an, Shaanxi, China., Zhang H; Department of Cardiothoracic and Vascular Surgery and Critical Care Medicine, Xi'an No.1 Hospital and The First Affiliated Hospital of Northwest University, Xi'an, Shaanxi, China., Yang B; Department of Cardiothoracic and Vascular Surgery and Critical Care Medicine, Xi'an No.1 Hospital and The First Affiliated Hospital of Northwest University, Xi'an, Shaanxi, China., Wu Y; Department of Cardiothoracic and Vascular Surgery and Critical Care Medicine, Xi'an No.1 Hospital and The First Affiliated Hospital of Northwest University, Xi'an, Shaanxi, China., Gao W; Department of Anesthesiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Hou Y; Department of Anesthesiology, Xi'an Chest Hospital and Northwest University Affiliated Chest Hospital, Xi'an, Shaanxi, China. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2026 Apr 30; Vol. 17, pp. 1695352. Date of Electronic Publication: 2026 Apr 30 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1663-9812 |
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| DOI: | 10.3389/fphar.2026.1695352 |
