Anti-β2GPI IgG display a broad reactivity against different β2GPI domains beyond domain 1: results from the APS ACTION and multi-center Italian cohorts.
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| Title: | Anti-β2GPI IgG display a broad reactivity against different β2GPI domains beyond domain 1: results from the APS ACTION and multi-center Italian cohorts. |
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| Authors: | Grossi C; Laboratory of Immuno-Rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy., Bodio C; Laboratory of Immuno-Rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy., Kumar S; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, United States., Bison E; Thrombosis Research Laboratory, Department of Cardio-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy., Cervera R; Department of Autoimmune Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain., Gerosa M; Dipartimento di Scienze Cliniche e di Comunità, University of Milan, Milan, Italy.; Dipartimento di Eccellenza, University of Milan, Milan, Italy.; Rheumatology Clinic, ASST-G.Pini-CTO, Milan, Italy., Mahler M; Research and Development, Headquarters & Technology Center Autoimmunity, Werfen, San Diego, CA, United States., Paredes-Ruiz D; Autoimmune Diseases Research Unit, Department of Internal Medicine, Biobizkaia Health Research Institute, Hospital Universitario, Cruces, Spain., Piantoni S; Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Department of Clinical and Experimental Sciences, University of Brescia, ERN-Reconnect Member, Brescia, Italy., Radin M; Department of Clinical and Biological Sciences, University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases (ERK-Net, ERN-Reconnect and RITA-ERN Member) with Nephrology and Dialysis Unit and Center of Immuno- Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hub Hospital, University of Turin, Turin, Italy., Sciascia S; Hospital Universitario 12 de Octubre, Madrid, Spain., Rodriguez-Almaraz E; Hospital Universitario 12 de Octubre, Madrid, Spain., Tektonidou MG; Rheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Tincani A; Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Department of Clinical and Experimental Sciences, University of Brescia, ERN-Reconnect Member, Brescia, Italy., Pengo V; Thrombosis Research Laboratory, Department of Cardio-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy., Soranna D; Biostatistic Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy., Zambon A; Biostatistic Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Laboratory of Quantitative Methods for Life, Health and Society, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy., Bertolaccini ML; Academic Department of Vascular Surgery, School of Cardiovascular and Metabolic Medicine & Sciences, King's College, London, United Kingdom., Cohen H; Department of Haematology, University College London, London, United Kingdom., Erkan D; Barbara Volcker Center for Women and Rheumatic Diseases, Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, United States., Pozzi N; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, United States., Tedesco F; Laboratory of Immuno-Rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy., Borghi MO; Laboratory of Immuno-Rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Dipartimento di Scienze Cliniche e di Comunità, University of Milan, Milan, Italy.; Dipartimento di Eccellenza, University of Milan, Milan, Italy., Meroni PL; Laboratory of Immuno-Rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy. |
| Source: | Frontiers in immunology [Front Immunol] 2026 May 01; Vol. 17, pp. 1809192. Date of Electronic Publication: 2026 May 01 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1809192 |