HDAC8 impairs tight junctions in allergic rhinitis through Smad7 deacetylation.

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Title: HDAC8 impairs tight junctions in allergic rhinitis through Smad7 deacetylation.
Authors: Chang HH; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Cao ZN; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Dang PH; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Wei M; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Li Y; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Zhang HP; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Wang J; Department of Otolaryngology-Head and Neck Surgery, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Source: Frontiers in immunology [Front Immunol] 2026 May 01; Vol. 17, pp. 1793810. Date of Electronic Publication: 2026 May 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1793810