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Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.

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Title: Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.
Authors: van de Bovenkamp AA; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Nassiri S; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., de Man FS; Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Oosterveer FPT; Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Mourmans SGJ; Department of Cardiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., van Raalte DH; Department of Internal Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Dijkmans PA; Department of Cardiology, Zaans Medisch Centrum, Zaandam, The Netherlands., van Heerebeek L; Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands., van Empel VPM; Department of Cardiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., Eringa EC; Department of Physiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.; Department of Physiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., Bakermans AJ; Department Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Handoko LM; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.; Department of Cardiology, Transplantation Center, UMC Utrecht, Utrecht, The Netherlands.
Source: European journal of heart failure [Eur J Heart Fail] 2026 May 18. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0844
DOI:10.1093/ejhf/xuag162