Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.

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Title: Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.
Authors: van de Bovenkamp AA; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Nassiri S; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., de Man FS; Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Oosterveer FPT; Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Mourmans SGJ; Department of Cardiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., van Raalte DH; Department of Internal Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Dijkmans PA; Department of Cardiology, Zaans Medisch Centrum, Zaandam, The Netherlands., van Heerebeek L; Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands., van Empel VPM; Department of Cardiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., Eringa EC; Department of Physiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.; Department of Physiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., Bakermans AJ; Department Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands., Handoko LM; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.; Department of Cardiology, Transplantation Center, UMC Utrecht, Utrecht, The Netherlands.
Source: European journal of heart failure [Eur J Heart Fail] 2026 May 18. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22van+de+Bovenkamp+AA%22">van de Bovenkamp AA</searchLink>; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nassiri+S%22">Nassiri S</searchLink>; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Man+FS%22">de Man FS</searchLink>; Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Oosterveer+FPT%22">Oosterveer FPT</searchLink>; Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mourmans+SGJ%22">Mourmans SGJ</searchLink>; Department of Cardiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Raalte+DH%22">van Raalte DH</searchLink>; Department of Internal Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijkmans+PA%22">Dijkmans PA</searchLink>; Department of Cardiology, Zaans Medisch Centrum, Zaandam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Heerebeek+L%22">van Heerebeek L</searchLink>; Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Empel+VPM%22">van Empel VPM</searchLink>; Department of Cardiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Eringa+EC%22">Eringa EC</searchLink>; Department of Physiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.; Department of Physiology, Maastricht UMC+, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bakermans+AJ%22">Bakermans AJ</searchLink>; Department Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Handoko+LM%22">Handoko LM</searchLink>; Department of Cardiology, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.; Department of Cardiology, Transplantation Center, UMC Utrecht, Utrecht, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22100887595%22">European journal of heart failure</searchLink> [Eur J Heart Fail] 2026 May 18. <i>Date of Electronic Publication: </i>2026 May 18.
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        Value: 10.1093/ejhf/xuag162
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              Text: 2026 May 18
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