NRF2 as a guardian of health: from an ancient survival pathway to a modern therapeutic target.

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Title: NRF2 as a guardian of health: from an ancient survival pathway to a modern therapeutic target.
Authors: Tenreiro S; iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, Portugal. Electronic address: stenreiro@nms.unl.pt., Falcão AS; iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, Portugal., Bender N; Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland., Bernatova I; Centre of Experimental Medicine, Slovak Academy of Sciences, Institute of Normal and Pathological Physiology, Bratislava, Slovakia., Berry A; Center for Behavioral Sciences and Mental Health, Instituto Superiore di Sanità, Rome, Italy., Cuadrado A; Department of Biochemistry, Medical College, Autonomous University of Madrid (UAM), Madrid, Spain., Eppenberger P; Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland., Giona L; Center for Behavioral Sciences and Mental Health, Instituto Superiore di Sanità, Rome, Italy; Faculty of Medicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy., Grochot-Przeczek A; Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Krakow, Krakow, Poland., Heiss E; Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria., Jakubowska M; Malopolska Centre of Biotechnology, Jagiellonian University in Krakow, Krakow, Poland., Long PF; Institute of Pharmaceutical Science, King's College London, London, United Kingdom; Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil., Makhro A; Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland., Masoodi M; Faculty of Medicine, University Hospital Bern, Switzerland., Morgenstern C; Vienna Airway Lab, Department of Otolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria., Saso L; Department of Physiology and Pharmacology 'Vittorio Erspamer', La Sapienza University, Rome, Italy., Seabra MC; iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, Portugal., Sznarkowska A; International Centre for Cancer Vaccine Science, University of Gdansk, Gdansk, Poland., Sykiotis G; Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Trougakos IP; Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Source: Redox biology [Redox Biol] 2026 Jul; Vol. 94, pp. 104217. Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2213-2317
DOI:10.1016/j.redox.2026.104217