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Improving the palatability of Platycodonic Radix for pediatric use: Integrating LC-MS-based bitter component profiling with an HP-β-Cyclodextrin/xylitol taste-masking strategy.

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Title: Improving the palatability of Platycodonic Radix for pediatric use: Integrating LC-MS-based bitter component profiling with an HP-β-Cyclodextrin/xylitol taste-masking strategy.
Authors: Zhou Z; Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovative Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Zhang S; Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovative Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Fang C; Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovative Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Cheng H; Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovative Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Yasheng M; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Yuan J; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Cai W; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Fang Z; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Wu F; Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovative Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China., Wang Y; Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Innovative Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China. Electronic address: shutcmyo@163.com., Xue Z; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China. Electronic address: shszyyyek@126.com., Zhang X; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, PR China. Electronic address: zhangxinguang111@126.com.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Jun 25; Vol. 699, pp. 126985. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-3476
DOI:10.1016/j.ijpharm.2026.126985