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Noninvasive in vivo imaging of NF-κB activation predicts immunotherapy response in solid tumors.

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Title: Noninvasive in vivo imaging of NF-κB activation predicts immunotherapy response in solid tumors.
Authors: Stowbur D; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany., Mehling R; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany., Knopf P; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany., Schörg BF; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany., Sonanini D; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.; Internal Medicine VIII, University Hospital of Tübingen, Tübingen, Germany., Arnold-Schild D; Institute of Immunology, University Medical Center Mainz, Mainz, Germany., Gonzalez-Menendez I; Core Facility Histology, Faculty of Medicine Tübingen, University Hospital Tübingen, Tübingen, Germany., Quintanilla-Martinez L; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.; Core Facility Histology, Faculty of Medicine Tübingen, University Hospital Tübingen, Tübingen, Germany., Fehrenbacher B; Department of Dermatology, Eberhard Karls University, Tübingen, Germany., Schaller M; Department of Dermatology, Eberhard Karls University, Tübingen, Germany., Carlsen H; Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway., Kumari S; Frazer Institute, Faculty of Health, Medicine and Behavioural Science, The University of Queensland, Brisbane, QLD, Australia.; Dermatology Research Centre, The University of Queensland, Brisbane, QLD, Australia., Pichler BJ; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center, Heidelberg, Germany., Kneilling M; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany. manfred.kneilling@med.uni-tuebingen.de.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany. manfred.kneilling@med.uni-tuebingen.de.; Department of Dermatology, Eberhard Karls University, Tübingen, Germany. manfred.kneilling@med.uni-tuebingen.de.
Source: Npj imaging [Npj Imaging] 2026 May 20; Vol. 4 (1). Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Switzerland NLM ID: 9918733285306676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-197X (Electronic) Linking ISSN: 2948197X NLM ISO Abbreviation: Npj Imaging Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Noninvasive in vivo imaging of NF-κB activation predicts immunotherapy response in solid tumors.
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  Data: <searchLink fieldCode="AU" term="%22Stowbur+D%22">Stowbur D</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Mehling+R%22">Mehling R</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Knopf+P%22">Knopf P</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schörg+BF%22">Schörg BF</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Sonanini+D%22">Sonanini D</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.; Internal Medicine VIII, University Hospital of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Arnold-Schild+D%22">Arnold-Schild D</searchLink>; Institute of Immunology, University Medical Center Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Menendez+I%22">Gonzalez-Menendez I</searchLink>; Core Facility Histology, Faculty of Medicine Tübingen, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Quintanilla-Martinez+L%22">Quintanilla-Martinez L</searchLink>; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.; Core Facility Histology, Faculty of Medicine Tübingen, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Fehrenbacher+B%22">Fehrenbacher B</searchLink>; Department of Dermatology, Eberhard Karls University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schaller+M%22">Schaller M</searchLink>; Department of Dermatology, Eberhard Karls University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Carlsen+H%22">Carlsen H</searchLink>; Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.<br /><searchLink fieldCode="AU" term="%22Kumari+S%22">Kumari S</searchLink>; Frazer Institute, Faculty of Health, Medicine and Behavioural Science, The University of Queensland, Brisbane, QLD, Australia.; Dermatology Research Centre, The University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Pichler+BJ%22">Pichler BJ</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kneilling+M%22">Kneilling M</searchLink>; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany. manfred.kneilling@med.uni-tuebingen.de.; Cluster of Excellence iFIT (EXC 2180) 'Image Guided and Functionally Instructed Tumor Therapies', Tübingen, Germany. manfred.kneilling@med.uni-tuebingen.de.; Department of Dermatology, Eberhard Karls University, Tübingen, Germany. manfred.kneilling@med.uni-tuebingen.de.
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