Chronic bisphenol A exposure activates the cGAS-STING-NLRP3 axis driving persistent hippocampal neuroinflammation and cognitive impairment.

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Title: Chronic bisphenol A exposure activates the cGAS-STING-NLRP3 axis driving persistent hippocampal neuroinflammation and cognitive impairment.
Authors: Tom VV; Department of Allied Health Sciences, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to Be University), Mangalore, Karnataka, 575018, India., Mallick S; Division of Molecular Genetics and Cancer, Nitte University Centre for Science Education and Research, Nitte (Deemed to be University), Karnataka, 575018, Mangalore, India., Sasidharan A; Department of Allied Health Sciences, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to Be University), Mangalore, Karnataka, 575018, India., Biswas T; Stem Cells and Regenerative Medicine Centre, Yenepoya Research Centre, Yenepoya (Deemed to Be University), University Road, Mangalore, Karnataka, 575018, India., Bose B; Stem Cells and Regenerative Medicine Centre, Yenepoya Research Centre, Yenepoya (Deemed to Be University), University Road, Mangalore, Karnataka, 575018, India. bipasha.bose@yenepoya.edu.in., Somayaji Y; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA. yogish_somayaji@tamu.edu., Fernandes R; Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to Be University), Mangalore, Karnataka, 575018, India. ronaldfernandes@nitte.edu.in.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2026 May 21. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-4919
DOI:10.1007/s11010-026-05580-4