TM5441, a PAI-1 inhibitor, attenuates chronic stress-induced anxio-depressive-like behaviors by restoring the hippocampal PAI-1/tPA/BDNF axis.
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| Title: | TM5441, a PAI-1 inhibitor, attenuates chronic stress-induced anxio-depressive-like behaviors by restoring the hippocampal PAI-1/tPA/BDNF axis. |
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| Authors: | Bahi A; Department of Basic Medical Sciences, College of Medicine, Ajman University, Ajman, UAE. a.bahi@ajman.ac.ae.; Center of Medical & Bio-Allied Health Sciences Research, Ajman University, Ajman, UAE. a.bahi@ajman.ac.ae., Dreyer JL; Division of Biochemistry, Department of Medicine, University of Fribourg, Fribourg, Switzerland. |
| Source: | Psychopharmacology [Psychopharmacology (Berl)] 2026 May 22. Date of Electronic Publication: 2026 May 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1432-2072 |
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| DOI: | 10.1007/s00213-026-07091-y |