Diacerein mitigates cisplatin-induced testicular toxicity in rats; Role of Nrf2/ HO-1, NF-κB/caspase-3 and NLRP3/ASC/Caspase-1 signaling pathways.

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Title: Diacerein mitigates cisplatin-induced testicular toxicity in rats; Role of Nrf2/ HO-1, NF-κB/caspase-3 and NLRP3/ASC/Caspase-1 signaling pathways.
Authors: Kamel GAM; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City, Cairo, 11754, PN, Egypt., Hussein S; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia. sshassan@ju.edu.sa.
Source: Molecular biology reports [Mol Biol Rep] 2026 May 22; Vol. 53 (1). Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Diacerein mitigates cisplatin-induced testicular toxicity in rats; Role of Nrf2/ HO-1, NF-κB/caspase-3 and NLRP3/ASC/Caspase-1 signaling pathways.
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  Data: <searchLink fieldCode="AU" term="%22Kamel+GAM%22">Kamel GAM</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City, Cairo, 11754, PN, Egypt.<br /><searchLink fieldCode="AU" term="%22Hussein+S%22">Hussein S</searchLink>; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia. sshassan@ju.edu.sa.
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  Data: <searchLink fieldCode="JN" term="%220403234%22">Molecular biology reports</searchLink> [Mol Biol Rep] 2026 May 22; Vol. 53 (1). <i>Date of Electronic Publication: </i>2026 May 22.
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        Value: 10.1007/s11033-026-12004-5
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        Text: English
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      – TitleFull: Diacerein mitigates cisplatin-induced testicular toxicity in rats; Role of Nrf2/ HO-1, NF-κB/caspase-3 and NLRP3/ASC/Caspase-1 signaling pathways.
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            NameFull: Kamel GAM
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              Text: 2026 May 22
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              Y: 2026
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