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Ergostatrien-3β-ol suppresses breast cancer anoikis resistance and metastasis by targeting the miR-93-5p/leupaxin axis.

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Title: Ergostatrien-3β-ol suppresses breast cancer anoikis resistance and metastasis by targeting the miR-93-5p/leupaxin axis.
Authors: Rengamanar H; Graduate Institute of Biological Science and Technology, China Medical University, Taichung, Taiwan., Chen WC; Department of Medicine, MacKay Medical University, New Taipei, Taiwan; Division of Sports Medicine & Surgery, Department of Orthopaedic Surgery, MacKay Memorial Hospital, Taipei, Taiwan., Kuo YH; Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan., Tsai HC; Department of Medicine Research, China Medical University Beigang Hospital, Yunlin, Taiwan., Fong YC; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan; Department of Orthopedic Surgery, China Medical University Beigang Hospital, Yunlin, Taiwan., Guo JH; Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan., Liu CL; Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan., Huang TM; Department of Chest Surgery, China Medical University Hospital, Taichung, Taiwan., Wu CY; School of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Neurosurgery, China Medical University Hsinchu Hospital, Hsinchu, Taiwan. Electronic address: 014345@tool.caaumed.org.tw., Tang CH; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan; Department of Medical Laboratory Science and Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan. Electronic address: chtang@mail.cmu.edu.tw.
Source: European journal of pharmacology [Eur J Pharmacol] 2026 Jul 10; Vol. 1029, pp. 179022. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ergostatrien-3β-ol suppresses breast cancer anoikis resistance and metastasis by targeting the miR-93-5p/leupaxin axis.
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  Data: <searchLink fieldCode="AU" term="%22Rengamanar+H%22">Rengamanar H</searchLink>; Graduate Institute of Biological Science and Technology, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+WC%22">Chen WC</searchLink>; Department of Medicine, MacKay Medical University, New Taipei, Taiwan; Division of Sports Medicine & Surgery, Department of Orthopaedic Surgery, MacKay Memorial Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+YH%22">Kuo YH</searchLink>; Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+HC%22">Tsai HC</searchLink>; Department of Medicine Research, China Medical University Beigang Hospital, Yunlin, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fong+YC%22">Fong YC</searchLink>; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan; Department of Orthopedic Surgery, China Medical University Beigang Hospital, Yunlin, Taiwan.<br /><searchLink fieldCode="AU" term="%22Guo+JH%22">Guo JH</searchLink>; Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+CL%22">Liu CL</searchLink>; Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+TM%22">Huang TM</searchLink>; Department of Chest Surgery, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CY%22">Wu CY</searchLink>; School of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Neurosurgery, China Medical University Hsinchu Hospital, Hsinchu, Taiwan. Electronic address: 014345@tool.caaumed.org.tw.<br /><searchLink fieldCode="AU" term="%22Tang+CH%22">Tang CH</searchLink>; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan; Department of Medical Laboratory Science and Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan. Electronic address: chtang@mail.cmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%221254354%22">European journal of pharmacology</searchLink> [Eur J Pharmacol] 2026 Jul 10; Vol. 1029, pp. 179022. <i>Date of Electronic Publication: </i>2026 May 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>1254354 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0712 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200142999%22">00142999 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharmacol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42191085
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        Value: 10.1016/j.ejphar.2026.179022
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              Text: 2026 Jul 10
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