Interpretation of Pharmacometabolomics Results: Fingerprint of Drug Exposure or Confounder Effects? Insights from a Urinary Metabolomics Study with Voriconazole in Healthy Participants.
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| Title: | Interpretation of Pharmacometabolomics Results: Fingerprint of Drug Exposure or Confounder Effects? Insights from a Urinary Metabolomics Study with Voriconazole in Healthy Participants. |
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| Authors: | Chobanyan-Jürgens K; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Pediatric Clinical-Pharmacological Trial Center (paedKliPS), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany., Muhareb A; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany., Niesert M; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Pediatric Clinical-Pharmacological Trial Center (paedKliPS), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany., Scherkl C; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany., Meid AD; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany., Cannet C; Bruker BioSpin GmbH & Co. KG, 76275 Ettlingen, Germany., Pituk D; Bruker BioSpin GmbH & Co. KG, 76275 Ettlingen, Germany., Hoffmann GF; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany., Stingl JC; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany., Ziegler A; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Pediatric Clinical-Pharmacological Trial Center (paedKliPS), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany., Blank A; Heidelberg University, Medical Faculty Heidelberg, Heidelberg University Hospital, Internal Medicine IX-Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany. |
| Source: | International journal of molecular sciences [Int J Mol Sci] 2026 May 16; Vol. 27 (10). Date of Electronic Publication: 2026 May 16. |
| Publication Type: | Journal Article; Clinical Trial |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1422-0067 |
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| DOI: | 10.3390/ijms27104468 |
