Immunological mechanisms and precision stratification in male infertility: from testicular immune privilege and danger signal amplification to seminal immune biomarkers and mechanism-tailored intervention.

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Title: Immunological mechanisms and precision stratification in male infertility: from testicular immune privilege and danger signal amplification to seminal immune biomarkers and mechanism-tailored intervention.
Authors: Zhou J; The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Urology, the First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Hu S; The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Urology, the First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Ouyang Y; The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Urology, the First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Yang D; The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Urology, the First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Su Z; The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Urology, the First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Liu M; The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Reproductive Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Source: Frontiers in immunology [Front Immunol] 2026 May 12; Vol. 17, pp. 1806683. Date of Electronic Publication: 2026 May 12 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1806683